Full Agenda

Identification and Functional Characterization of Adhesion GPCRs As Steroid Hormone Receptors and Hearing and Balance Receptors

Self-Cleavage of GPR110 SEA Domain and Its Impact on GAIN Domain Autoproteolysis

Heterogeneity of Tethered Agonist Signaling in Adhesion G Protein-Coupled Receptors

Site Specific N-Glycosylation Of The N-Terminal Fragment Of ADGRG6 Drives Proteolytic Processing, Trafficking And Signalling

Characterizing hADGRE5/CD97 Activation and Signaling: A Mechanical Stimulation BRET-Based Approach (MS-BRET)

Unveiling the GPS Cleavage Mechanism in ADGRL1 with QM/MM

The Adhesion GPCR Latrophilin Interacts With The Notch Pathway To Control Germ Cell Proliferation

The CELSR/ADGRC Homolog Flamingo Is Not Autoproteolytically Processed By The GAIN Domain

Novel isoforms of adhesion G protein coupled receptor B1 (ADGRB1/BAI1) generated from an alternative promoter in intron 17

GPR124 Mediates Adhesion Of Leukemic Stem Cells To Their Niche And Leads To Myeloid Skewing

Anti-Tumorigenic Role of Brain Angiogenesis Inhibitor 3 (BAI3) in WNT-Activated Medulloblastomas

Conformational And Functional Coupling Between Extracellular and Transmembrane Regions of a Holo-Adhesion GPCR

Discriminating between the extracellular scaffolding and G protein signaling roles of GPR56/ADGRG1 via the characterization of a non-cleavable point mutant knock-in mouse, H381S

Adhesion GPCR BAI1/ADGRB1 can block IGF1R-mediated growth signalling, increase radiosensitivity and augment survival in medulloblastoma.

bioSens-All: A Multiparametric BRET-Based Platform for Comprehensive Profiling of adhesion GPCR Signaling and Pharmacology-Enabling Drug Discovery

Structural Determinants Of GAIN Domain Autoproteolysis And Cleavage Resistance Of Adhesion G Protein-Coupled Receptors

Uncovering the signaling pathway of the ADGRA homolog Remoulade in Drosophila

ADGRF5-mediated regulation of cardiac health and disease

Adgrg6/Gpr126 is Required for Myocardial Notch Activity and N-cadherin Localization to Attain Trabecular Identity

GAIN Domain Dynamics And Its Relevance For Adhesion GPCR Signaling In Vivo

Interrogating The Role Of CELSR1 (ADGRC1) In Breast Cancer

GPR110 modulates anxiety-like behaviors and memory function in mice potentially through neuronal and neuroimmune alterations during neurodevelopment

Signaling Properties of ADGRL3

The ADGRF5/GPR116 receptor is a key regulator of lymphatic endothelial cell identity and function

Bai1 Is A Novel Neuronal Substrate Of The Psychiatric Risk Kinase TNIK

Structural studies of the CELSR1 extracellular region reveal a compact multidomain module of fourteen domains which regulates signaling

Adhesion G protein-coupled receptor latrophilin-3 (ADGRL3) modulation of dopaminergic neurotransmission

Adhesion GPCR GPR116/Adgrf5 controls a lineage of anti-thermogenic adipocytes with implications for adaptive thermogenesis during prolonged cold exposure

Next Generation MBD2 inhibitors for Brain Cancer Therapy

Identification of Differentially Expressed Gpr116 (Adgrf5) Transcript Variants in Mouse Kidney

Endocytic Cues Determine the Signaling Profile of Adhesion GPCR ADGRL1 / Latrophilin-1

Generation and characterization of collecting duct specific GPR56 knockout mice

An ECR-Mediated and TA-independent Mechanism of aGPCR Activation: Direct Communication of Extracellular Region with Transmembrane Domain in a Holo-Adhesion GPCR

Localization of putative ligands for adhesion G protein-coupled receptors in mouse tissues.

BAI1/ADGRB1-mediated Regulation of Mitochondrial Morphology in Axons

ADGRCs in glutamatergic synapse formation, maintenance and degeneration

ADGRG1/GPR56 regulates survival of terminally differentiated CD8+ T cells

The Adhesion GPCR Cupidon Regulates Mating In The Closest Relatives Of Animals

Investigating The Role of ADGRB3 Loss of Expression in Brain Tumor Formation in Li-Fraumeni Syndrome

Elucidating The Role Of GPR97/ADGRG3 In Neutrophil Biology

Deorphanization Of The Adhesion GPCRs GPR110 and GPR116

Tethered Agonist Dependent ADGRL3 Signaling Activity In The G12/13 Pathway

Tethered Peptide Activation Mechanism of Adhesion GPCRs

The NTF Release Sensor Approach for Drug Discovery for Human Adhesion GPCRs

Intricacies Of Complex Assembly And Ligand Interaction In The Adhesion GPCR Latrophilin/Cirl

Antibody-drug conjugates targeting CD97 in glioblastoma

Critical role for CD97/ADGRE5 in the induction of allergic airway inflammation

Characterization of Phenotypes Associated with GPR110 Deletion

A single cell GPCR map of thermogenic fat

NovoiSMART - A new platform for GPCR antibody drug discovery