Activation and signaling characteristics of the hydroxy-carboxylic acid 3 receptor identified in human neutrophils through a microfluidic flow cell technique

GPCR Binders, Drugs, and more

April 1, 2025

Identification of anti-resorptive GPCRs by high-content imaging in human osteoclasts

April 7, 2025

Synthesis and Characterization of Photoswitchable Covalent Ligands for the β2-Adrenoceptor

April 4, 2025

Minimal Structural Variation of GPR84 Full Agonist Causes Functional Switch to Inverse Agonism

GPCRs in Cardiology, Endocrinology, and Taste

April 1, 2025

DRD2-Mediated AMPK Ubiquitination Regulates the Occurrence of Hepatic Steatosis

March 29, 2025

Genomic insights into ORs gene family of G protein-coupled receptors expansion driving omnivorous feeding in Spotted knifejaw (Oplegnathus punctatus)

April 3, 2025

Formyl-peptide receptor type 2 activation mitigates heart and lung damage in inflammatory arthritis

GPCRs in Neuroscience

March 31, 2025

Neurokinin 3 receptor agonist senktide stimulates GnRH release in isolated hypogonadotropic hypogonadism mice

April 1, 2025

Evidence for Bxy-npr-21 on controlling juveniles' growth and modulating male sexual arousal: from molecules to behaviors

April 1, 2025

Characterization of Anthozoan-Specific Opsins from a Reef-Building Coral, Acropora tenuis, as Gq-Coupled Opsins

GPCRs in Oncology and Immunology

April 10, 2025

SIGMAR1 screened by a GPCR-related classifier regulates endoplasmic reticulum stress in bladder cancer

April 7, 2025

G-protein coupled receptors in metabolic reprogramming and cancer

April 4, 2025

Unveiling the Role of DPYS: A New Prognostic Biomarker in Sarcoma

Methods & Updates in GPCR Research

April 7, 2025

Topology-Driven Negative Sampling Enhances Generalizability in Protein-Protein Interaction Prediction

April 7, 2025

A new approach to psoriasis therapy: photoswitchable A3 adenosine receptor activation

March 29, 2025

Sensitive detection of pertussis toxin in acellular pertussis vaccines using HRH1-mediated calcium signaling

Reviews, GPCRs, and more

April 9, 2025

Where are we now? Biased signalling of Class B G protein-coupled receptor-targeted therapeutics

April 1, 2025

Opioid Analgesics: Rise and Fall of Ligand Biased Signaling and Future Perspectives in the Quest for the Holy Grail

April 1, 2025

G Protein-Coupled Receptors in Skin Aging

Structural and molecular insights into GPCR function

April 3, 2025

Proton perception and activation of a proton-sensing GPCR

April 9, 2025

Molecular Dynamics (MD) Simulation of GPR87-LPA Binding: Therapeutic Implications for Targeted Cancer Treatment

April 4, 2025

Structural basis and biased signaling of proton sensation by GPCRs mediated by extracellular histidine rearrangement

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