Development of GPCR Ligands as Therapeutic Drugs

In addition to finding beneficial therapeutic activity in new GPCR drug candidates, it is essential that these molecules be useful of drug therapy and thus must be absorbed into the human body, distribute to where they are needed, remain there long enough to be therapeutic and cause no harm. This course will discuss the assays and techniques needed to ensure this profile.

Major topics or modules the workshop will cover:

1. The Essentials of New Drug Development

   1. Key Elements of Pharmacokinetics

   2. The Druglike Quality of Chemical Entities

   3. Drug Absorption