🎯 Crack the code of GPCR ligand development!

In case you haven’t heard, Dr. Terry Kenakin is hosting a 4-week course on GPCR drug development—and registration closes in 3 days! ⚠️

What you’ll learn:✅ Drug absorption, metabolism & clearance✅ PK-PD modeling & therapeutic profiles✅ Early safety assessments & toxicity risks

📌 Limited spots—sign up before March 18th! 👉 Development of GPCR Ligands as Therapeutic Drugs | Dr. GPCR Ecosystem 

#GPCR #DrGPCR #Pharma #Biotech #Research

🚨 Exciting Opportunity for Professionals in Drug Development! 🚨

Register today for a one-of-a-kind online course at Dr. GPCR University: "Development of GPCR Ligands as Therapeutic Drugs."

🗓 Dates: March 20 - April 10, 2025

⏰ Time: Thursdays, 10:00 AM - 11:30 AM (EST)

This advanced course is essential for anyone working in drug development and focuses on:

The essentials of new drug development

Key pharmacokinetic elements (absorption, distribution, clearance)

Hepatic metabolism and the Cytochrome P450 system

Drug safety and toxicology (including drug-drug interactions)

And much more!

Gain deep insights into GPCR drug candidates and learn the critical assays and techniques required to bring therapeutic molecules to life.

🚨 Only 25 spots available — register now!

💡 This is a great opportunity for both academia and industry professionals. Sessions will be live, and you’ll also have 1:1 discussion time with the instructor. Full PDFs of the slides will be available!

🔗 https://buff.ly/lVEcRUc

#GPCR #DrugDevelopment #Pharmacokinetics #TherapeuticDrugs #OnlineCourse #DrGPCRUniversity #PharmaceuticalIndustry

🔬 Enhance Your GPCR Expertise with Dr.GPCR University!

Looking to sharpen your skills in GPCR pharmacology, drug discovery, data analysis, or project management? Dr.GPCR University offers industry-focused courses designed to help you stay ahead in the field.

✅ Comprehensive course library covering cutting-edge GPCR science✅ Practical insights for real-world drug discovery challenges✅ Flexible, on-demand learning to fit your schedule

🚀 Elevate your expertise today: Start learning now

#GPCR #Pharmacology #DrugDiscovery #Biotech #DrGPCR

Did you know that A2B adenosine receptor-triggered calcium mobilization varies by cell type? A recent study explores how Gi, Gq, Gs proteins, and PKC contribute differently to intracellular Ca²⁺ signaling, revealing a more complex regulation than previously thought.

Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox

➡️https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/a2b-adenosine-receptor-triggered-intracellular-calcium-mobilization%3A-cell-type-dependent-involvement-of-gi%2C-gq%2C-gs-proteins-and-protein-kinase-c

#gpcr #drgpcr #metabolism #obesity

⏳ In case you haven’t heard—registration for “Development of GPCR Ligands as Therapeutic Drugs” closes March 18th!

If you’re working on GPCR drug discovery, you know that finding a promising candidate is just the start. A drug must also:✅ Be absorbed into the body✅ Reach the right target✅ Stay long enough to be effective✅ Cause no harm

📢 Spots are limited—register by March 18th! 👉 Development of GPCR Ligands as Therapeutic Drugs | Dr. GPCR Ecosystem  

#GPCR #DrGPCR #Pharmacology #Biotech #DrugDiscovery

💡 GPCR drug development doesn’t have to be a mystery! Learn from Dr. Terry Kenakin in this 4-week immersive course covering ligand development & pharmacology.

🔹 What you’ll learn:✅ Drug Development Basics – Absorption, metabolism, PK principles✅ Clearance & Distribution – Renal & hepatic clearance, key pharmacokinetics✅ PK-PD Modeling – Predicting drug behavior, non-linear PK✅ Early Drug Safety – Toxicity risks & drug interactions

📌 Spots are filling fast! Sign up today 👉 Development of GPCR Ligands as Therapeutic Drugs | Dr. GPCR Ecosystem  

#GPCR #DrGPCR #Pharmacology #Biotech #DrugDiscovery

📢 All 2025 Dr.GPCR Courses Are Open for Registration!

Which one will you choose? 🚀 Whether you're diving into GPCR drug discovery, pharmacology, or advanced modeling, there's a course for you.

💡 Bonus: Premium Members enjoy 25% off on all courses!

🔗 Explore & register today: https://www.ecosystem.drgpcr.com/gpcr-courses 

#GPCR #DrGPCR #Biotech #DrugDiscovery #Pharmacology

🚀 New Workshop: Practical Quantification of Allosteric Modulation

Join Dr. Terry Kenakin on May 1st, 2025, for an advanced live workshop on allosteric modulators in GPCR drug discovery.

Learn how to:✔️ Identify, measure, and quantify allosteric properties✔️ Apply functional allosteric models to determine mechanisms of action✔️ Confirm allostery through kinetic analysis

📅 Date: May 1st, 2025⏳ Registration deadline: April 18th📍 Live on Google Meet

🔗 Register now: https://www.ecosystem.drgpcr.com/event-details-registration/practical-quantification-of-allosteric-modulation 

#GPCR #Allostery #DrugDiscovery #Pharmacology

Did you know that GPR180 helps regulate lipid metabolism and may play a role in preventing obesity?  recent study shows that overexpression of GPR180 in adipose tissue improves lipid metabolism and protects against HFD-induced obesity, while its knockout worsens lipid accumulation. This finding highlights GPR180 as a potential therapeutic target for metabolic disorders!

Catch up on this exciting research in the Ecosystem today! 🏆📖 You’ll need to register, but don’t worry—it’s free!

➡️https://www.ecosystem.drgpcr.com/gpcrs-in-cardiology-endocrinology-and-taste/gpr180-reduces-adiposity-by-inhibiting-lipogenesis-and-fatty-acid-uptake-in-adipocytes 

#gpcr #drgpcr #metabolism #obesity

🚀 Ready to dive into the world of GPCR drug development? Join Dr. Terry Kenakin for the 4-week course “Development of GPCR Ligands as Therapeutic Drugs”! Get exclusive access to expert lectures, recordings, reading materials, and even a private call with Dr. Kenakin himself! Don’t miss this chance to level up your knowledge. 🔹 Spots are limited—save yours now! 👉 https://www.ecosystem.drgpcr.com/event-details-registration/development-of-gpcr-ligands-as-therapeutic-drugs  #gpcr #drgpcr #pharmacolgy #drugdiscovery #research

🚀 New Learning Opportunities at Dr.GPCR University! Expand your GPCR expertise with exclusive workshops, interactive courses, and an on-demand library—all in one place! ✅ Register for upcoming sessions ✅ Access expert-led content anytime ✅ Enjoy premium benefits & exclusive resources 📢 Don’t miss out—start your learning journey today! 🔗 https://www.ecosystem.drgpcr.com/gpcr-courses #GPCR #DrGPCR #LifelongLearning #drugdiscovery #pharmacology

🔥 New Course Alert! “Development of GPCR Ligands as Therapeutic Drugs” with Dr. Terry Kenakin is here! Spots are filling up fast—Premium Members get 25% off! This advanced course is exclusively available in the Ecosystem, so don’t miss your chance to learn from the best. 🔹 Secure your spot now! 👉 https://www.ecosystem.drgpcr.com/event-details-registration/development-of-gpcr-ligands-as-therapeutic-drugs  #gpcr #drgpcr #pharmacolgy #drugdiscovery #research

In case you haven’t heard, registrations are open for the next 4-week course “Development of GPCR Ligands as Therapeutic Drugs,” with Dr. Terry Kenakin 👏 Spots are filling up fast, run and save yours, and enjoy a 25% discount with your Premium Membership 🚀 

✳️Go to https://www.ecosystem.drgpcr.com/event-details-registration/development-of-gpcr-ligands-as-therapeutic-drugs 

#gpcr #drgpcr

An opportunity you won’t want to miss! ⚠️ The next 4-week course with Dr. Terry Kenakin, “Development of GPCR Ligands as Therapeutic Drugs” is coming up 🧐

Be the first to register, save your spot, and spread the word. This event will only happen once this year!

✳️Go to https://www.ecosystem.drgpcr.com/event-details-registration/development-of-gpcr-ligands-as-therapeutic-drugs for more information!

#gpcr #drgpcr

Did you know registrations are already open for all our 2025 Dr.GPCR University Courses? Check out what you can learn this year from the master, Dr. Terry Kenakin 😉and save your spot soon! Remember Premium Members get a 25% discount 🙌

✳️ Click here and start your next learning experience https://www.ecosystem.drgpcr.com/gpcr-courses

#gpcr #drgpcr

Game-changer for GPCR research! 🔬🧪 Molecular glues offer a new way to fine-tune receptor signaling, opening doors for next-gen drug discovery

Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox

➡️https://www.ecosystem.drgpcr.com/reviews/molecular-glues%3A-a-new-approach-to-modulating-gpcr-signaling-bias 

#gpcr #drgpcr

The registration deadline for the 1-day workshop “The Practical Assessment of Signaling Bias” is TOMORROW! ⏰ Save your spot in a class with the Master of Pharmacology Dr. Terry Kenakin, and get 25% off with your Premium Membership.

An advanced lecture, hands-on exercises, one private call with the professor, and more!

✳️Click here https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias 

#gpcr #drgpcr

⚠️ Registration Deadline today! This is your last chance to register for “The Practical Assessment of Signaling Bias” with Dr. Terry Kenakin. Learn theoretical background for the techniques and apply with hands-on exercises 💪

✳️ Last chance!!! https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias 

#gpcr #drgpcr

Did you know that GPR20, a potential therapeutic target to treat gastrointestinal stromal tumours, performs high constitutive activity when coupling with Gi? Check out this paper to see how molecular dynamics simulation can be used to explore its constitutive activation mechanism.

Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! 

➡️https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/exploring-the-constitutive-activation-mechanism-of-the-class-a-orphan-gpr20 

#gpcr #drgpcr

What do you want to learn today? If you’re an Ecosystem Member, you can learn something new every day! 🚀 Take one of our courses On-Demand and expand your knowledge of GPCRs.

✳️Discover your next learning experience at https://www.ecosystem.drgpcr.com/gpcr-courses 

#gpcr #drgpcr

The GPCR world is waiting to see YOU. Update your profile today and be part of the biggest GPCR community in the world 🌏

✳️ Visit https://www.ecosystem.drgpcr.com/account/my-account and share your updated information 😉

#gpcr #drgpcr

GPCR activation is well-known to be a multi-step process. However, current molecular structures only capture the fully activated complex. Check out this paper to see how scientists combine different techniques to elucidate the intermediate GPCR-mini-Gαsβγ complex at 2.6 Å. 

Did you know that we work hard to bring you the most recent GPCR News, weekly? Catch up today in the Ecosystem using your free site membership!

➡️https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/structure-and-function-of-a-near-fully-activated-intermediate-gpcr-g%CE%B1%CE%B2%CE%B3-complex 

#gpcr #drgpcr

Interested in learning more about signaling bias? You’re in the right place! 🙌 Join an interactive workshop with the pharmacology master Dr. Terry Kenakin and deepen your knowledge. Reading materials are already available for registered participants 👀

✳️ Go to https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias 

#gpcr #drgpcr

Seeking to gain more knowledge on signaling bias? We’ve got the perfect opportunity for you 🚀 Registrations open until February 14th

⚠️ Last spots available for “The Practical Assessment of Signaling Bias” with Dr. Terry Kenakin

✳️Register today at https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias

#gpcr #drgpcr

Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox

Unlocking the activation process of PTH1R: New computational insights into its molecular interactions bring us closer to better osteoporosis treatments!

➡️https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/key-interaction-changes-determine-the-activation-process-of-human-parathyroid-hormone-type-1-receptor 

#gpcr #drgpcr