Chronic itch: emerging treatments following new research concepts
Until recently, itch pathophysiology was poorly understood and treatments were poorly effective in relieving itch. Current progress in...
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GPCR News
Dec 1, 20211 min read
On-cell nuclear magnetic resonance spectroscopy to probe cell surface interactions
Nuclear magnetic resonance (NMR) spectroscopy allows the determination of atomic-level information on intermolecular interactions,...
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GPCR News
Dec 1, 20211 min read
4GPCRnet - International Symposium
SEPTEMBER 26-29, 2022 (Leipzig, Germany) 4GPCRnet meeting bringing together four of the biggest GPCR networks in Europe for a joint...
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GPCR News
Dec 1, 20211 min read
TLR4 biased small molecule modulators
Biased pharmacological modulators provide potential therapeutic benefits, including greater pharmacodynamic specificity, increased...
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GPCR News
Dec 1, 20211 min read
Meet Peter McNamara, Ph.D., Tectonic’s SVP, Head of Research
December 2021 "Meet Peter McNamara, Ph.D., Tectonic’s SVP, Head of Research. Peter joined Tectonic to help chart new territory in GPCR...
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GPCR News
Dec 1, 20211 min read
The development of modulators for lysophosphatidic acid receptors: A comprehensive review
Lysophosphatidic acids (LPAs) are bioactive phospholipids implicated in a wide range of cellular activities that regulate a diverse array...
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GPCR News
Dec 1, 20211 min read
Coordinated transcriptomics and peptidomics of central nervous system identify neuropeptides and ...
Coordinated transcriptomics and peptidomics of central nervous system identify neuropeptides and their G protein-coupled receptors in the...
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GPCR News
Dec 1, 20211 min read
Odorant G protein-coupled receptors as potential therapeutic targets for adult diffuse gliomas ...
Odorant G protein-coupled receptors as potential therapeutic targets for adult diffuse gliomas: a systematic analysis and review Odorant...
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GPCR News
Dec 1, 20211 min read
TeachOpenCADD - A teaching platform for computer-aided drug design
Open source programming packages for cheminformatics and structural bioinformatics are powerful tools to build modular, reproducible, and...
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GPCR News
Dec 1, 20211 min read
Sosei Heptares Announces Antitrust Clearance of License Agreement with Neurocrine Biosciences
December 2021 "Tokyo, Japan and Cambridge, UK, 24 December 2021 – Sosei Group Corporation (“Sosei Heptares”; TSE: 4565) today announces...
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GPCR News
Dec 1, 20211 min read
Melatonin MT 2 receptor is expressed and potentiates contraction in human airway smooth muscle
Nocturnal asthma is characterized by heightened bronchial reactivity at night, and plasma melatonin concentrations are higher in patients...
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GPCR News
Dec 1, 20211 min read
G protein-coupled receptor kinase 2 is essential to enable vasoconstrictor-mediated arterial ...
G protein-coupled receptor kinase 2 is essential to enable vasoconstrictor-mediated arterial smooth muscle proliferation Hypertension is...
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GPCR News
Nov 30, 20211 min read
Addex Raises $10 Million In Equity Financing
December 2021 "Geneva, Switzerland, December 17, 2021 – Addex Therapeutics Ltd (SIX: ADXN and Nasdaq: ADXN), a clinical-stage...
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GPCR News
Nov 30, 20211 min read
Trevena Announces Advancement of TRV045 Into Clinical Development for Diabetic Neuropathic Pain
December 2021 "3-part randomized, double-blind, placebo-controlled Phase 1 study will evaluate TRV045 safety, tolerability, and PK in...
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GPCR News
Nov 30, 20211 min read
Perkins’ Head of Molecular Endocrinology and Pharmacology, Professor Kevin Pfleger, was appointed...
December 2021 Perkins’ Head of Molecular Endocrinology and Pharmacology, Professor Kevin Pfleger, was appointed President of the...
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GPCR News
Nov 30, 20211 min read
VIB spin-off Confo Therapeutics Enters Collaborative Agreement with Regeneron
December 2021 "30/11/2021 Confo will work together with Regeneron to apply its GPCR drug discovery platform to enable functional antibody...
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GPCR News
Nov 30, 20211 min read
Crinetics Pharmaceuticals announced the formation of an independently operated new company...
December 2021 Crinetics Pharmaceuticals announced the formation of an independently operated new company, Radionetics Oncology....
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GPCR News
Nov 30, 20211 min read
Orion Announces The Rapid Lead Optimization Of Ob-004 - A Ccr2 Antagonist
December 2021 "Ottawa, Ontario, Canada, Nov. 30, 2021 -- Orion Biotechnology, a clinical stage company unlocking the therapeutic...
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GPCR News
Nov 30, 20211 min read
Neurocrine Biosciences Announces Positive Phase 3 Data for KINECT-HD Study Evaluating Valbenazine...
December 2021 Neurocrine Biosciences Announces Positive Phase 3 Data for KINECT-HD Study Evaluating Valbenazine for Chorea Associated...
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GPCR News
Nov 30, 20211 min read
First in Human: Early-stage COVID therapies hold promise against omicron variant
December 2021 "Early-stage studies of COVID-19 treatments from the likes of Vir Biotechnology Inc. and Trevena Inc. could offer potential...
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