GPCR News 

Glucagon receptor-mediated regulation of gluconeogenic gene transcription is endocytosis-dependent..

Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin...

Mechanistic Understanding of the Palmitoylation of Go Protein in the Allosteric Regulation of...

Production of human A2AAR in lipid nanodiscs for 19F-NMR and single-molecule fluorescence...

Activation of GPR183 by 7 α,25-Dihydroxycholesterol Induces Behavioral Hypersensitivity through...

Use of CRISPR/Cas9-edited HEK293 cells reveals that both conventional and novel protein kinase C...

N-Acyl Amides from Neisseria meningitidis and Their Role in Sphingosine Receptor Signaling

Function and structure of bradykinin receptor 2 for drug discovery

Specific Functions of Melanocortin 3 Receptor (MC3R)

Viral G Protein-Coupled Receptors Encoded by β- and γ-Herpesviruses

β-arrestin1 and 2 exhibit distinct phosphorylation-dependent conformations when coupling to the...

The complicated lives of GPCRs in cardiac fibroblasts

Differences across sexes on head-twitch behavior and 5-HT2A receptor signaling in C57BL/6J mice

Adrenal G Protein-Coupled Receptors and the Failing Heart: A Long-distance, Yet Intimate Affair

GB83, an Agonist of PAR2 with a Unique Mechanism of Action Distinct from Trypsin and PAR2-AP

GPR125 (ADGRA3) is an autocleavable adhesion GPCR that traffics with Dlg1 to the basolateral...

Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5

Comparative studies of AlphaFold, RoseTTAFold and Modeller: a case study involving the use of...

The Adhesion GPCR VLGR1/ADGRV1 Regulates the Ca2+ Homeostasis at Mitochondria-Associated ER Membrane

Mechanism of enhanced sensitivity of mutated β-adrenergic-like octopamine receptor to amitraz in...