GPCR News 

To probe the activation mechanism of the Delta opioid receptor by an agonist ADL5859 started from...

Novel Driver Strength Index highlights important cancer genes in TCGA PanCanAtlas patients

β2-Adrenergic Receptor Expression and Intracellular Signaling in B Cells Are Highly Dynamic during..

Structural basis for receptor selectivity and inverse agonism in S1P5 receptors

Statin-induced increase in actin polymerization modulates GPCR dynamics and compartmentalization

Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify...

Roles of Focal Adhesion Kinase PTK2 and Integrin αIIbβ3 Signaling in Collagen- and GPVI-Dependent...

Cell Surface Calcium-Sensing Receptor Heterodimers: Mutant Gene Dosage Affects Ca 2+ Sensing but...

Although the cannabinoid type-2 receptor (CB2) is highly expressed in the immune system, emerging...

A Setmelanotide-like Effect at MC4R Is Achieved by MC4R Dimer Separation

A2B Adenosine Receptor Enhances Chemoresistance of Glioblastoma Stem-Like Cells under Hypoxia: New..

Functional modulation of PTH1R activation and signaling by RAMP2

High GPER expression in triple-negative breast cancer is linked to pro-metastatic pathways and...

Lipid Modulation of a Class B GPCR: Elucidating the Modulatory Role of PI(4,5)P 2 Lipids

A broad look into the future of systemic sclerosis

Ligands can differentially and temporally modulate GPCR interaction with 14-3-3 isoforms

GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation

Computational study of the conformational ensemble of CX3C chemokine receptor 1 (CX3CR1) and its...

Fly casting with ligand sliding and orientational selection supporting complex formation of a GPCR..

Dimerization of GPCRs: Novel insight into the role of FLNA and SSAs regulating SST2 and SST5...