Emerging approaches for decoding neuropeptide transmission
GPCR News
Location bias contributes to functionally selective responses of biased CXCR3 agonists
Deciphering the signaling mechanisms of β-arrestin1 and β-arrestin2 in regulation of cancer cell...
Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5
Structural insights into adhesion GPCR ADGRL3 activation and Gq, Gs, Gi, and G12 coupling
Conservation of Allosteric Ligand Binding Sites in G-Protein Coupled Receptors
Dimerization of β2-adrenergic receptor is responsible for the constitutive activity subjected to inv
High hedgehog signaling is transduced by a multikinase-dependent switch controlling the...
Structure of the vasopressin hormone-V2 receptor-β-arrestin1 ternary complex
Dual loss of regulator of G protein signaling 2 and 5 exacerbates ventricular myocyte arrhythmias...
Mechanistic basis of GPCR activation explored by ensemble refinement of crystallographic structures
Increased Anxiety-like Behaviors in Adgra1-/- Male But Not Female Mice are Attributable to...
Dimerization of β2-adrenergic receptor is responsible for the constitutive activity subjected to...
Structural view of G protein-coupled receptor signaling in the retinal rod outer segment
Case Report of a Juvenile Patient with Autism Spectrum Disorder with a Novel Combination of Copy...
Discovery and In Vivo Evaluation of ACT-660602: A Potent and Selective Antagonist of the Chemokine..
Recurrent hypoglycemia increases hepatic gluconeogenesis without affecting glycogen metabolism or sy
Reversible Photocontrol of Dopaminergic Transmission in Wild-Type Animals
Nanobodies as Probes and Modulators of Cardiovascular G Protein-Coupled Receptors
Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling