GPCR News 

Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify...

Roles of Focal Adhesion Kinase PTK2 and Integrin αIIbβ3 Signaling in Collagen- and GPVI-Dependent...

Cell Surface Calcium-Sensing Receptor Heterodimers: Mutant Gene Dosage Affects Ca 2+ Sensing but...

Although the cannabinoid type-2 receptor (CB2) is highly expressed in the immune system, emerging...

A Setmelanotide-like Effect at MC4R Is Achieved by MC4R Dimer Separation

A2B Adenosine Receptor Enhances Chemoresistance of Glioblastoma Stem-Like Cells under Hypoxia: New..

Functional modulation of PTH1R activation and signaling by RAMP2

High GPER expression in triple-negative breast cancer is linked to pro-metastatic pathways and...

Lipid Modulation of a Class B GPCR: Elucidating the Modulatory Role of PI(4,5)P 2 Lipids

A broad look into the future of systemic sclerosis

Ligands can differentially and temporally modulate GPCR interaction with 14-3-3 isoforms

GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation

Computational study of the conformational ensemble of CX3C chemokine receptor 1 (CX3CR1) and its...

Fly casting with ligand sliding and orientational selection supporting complex formation of a GPCR..

Dimerization of GPCRs: Novel insight into the role of FLNA and SSAs regulating SST2 and SST5...

Cholesterol occupies the lipid translocation pathway to block phospholipid scrambling by a GPCR

Propranolol: A “Pick and Roll” Team Player in Benign Tumors and Cancer Therapies

Integrative model of the FSH receptor reveals the structural role of the flexible hinge region

A central alarm system that gates multi-sensory innate threat cues to the amygdala

Cholesterol-Dependent Dynamics of the Serotonin 1A Receptor Utilizing Single Particle Tracking....