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GPCR News
Sep 1, 20221 min read
Structure of Mycobacterium tuberculosis Cya, an evolutionary ancestor of the mammalian membrane...
September 2022 Structure of Mycobacterium tuberculosis Cya, an evolutionary ancestor of the mammalian membrane adenylyl cyclases...
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GPCR News
Sep 1, 20221 min read
Ginsenoside Rg5 allosterically interacts with P2RY12 and ameliorates deep venous thrombosis by...
September 2022 Ginsenoside Rg5 allosterically interacts with P2RY12 and ameliorates deep venous thrombosis by counteracting neutrophil...
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GPCR News
Sep 1, 20221 min read
C5aR2 receptor: The genomic twin of the flamboyant C5aR1
September 2022 "The complement fragment C5a is one of the most potent proinflammatory glycoproteins liberated by the activation of the...
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GPCR News
Sep 1, 20221 min read
C1-inhibitor influence on platelet activation by thrombin receptors agonists
September 2022 "Introduction Protease activated receptors 1 (PAR1) and 4 (PAR4) agonists are used to study platelet activation. Data on...
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GPCR News
Sep 1, 20221 min read
Residency time of agonists does not affect the stability of GPCR-arrestin complexes
September 2022 "Background and purpose: The interaction of arrestins with G-protein coupled receptors (GPCRs) desensitizes...
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GPCR News
Sep 1, 20221 min read
Cell-Type-Specific Effects of the Ovarian Cancer G-Protein Coupled Receptor (OGR1) on Inflammation..
September 2022 Cell-Type-Specific Effects of the Ovarian Cancer G-Protein Coupled Receptor (OGR1) on Inflammation and Fibrosis; Potential...
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GPCR News
Sep 1, 20221 min read
The Gluopsins: Opsins without the Retinal Binding Lysine
September 2022 "Opsins allow us to see. They are G-protein-coupled receptors and bind as ligand retinal, which is bound covalently to a...
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GPCR News
Sep 1, 20221 min read
Multifunctional role of GPCR signaling in epithelial tube formation
September 2022 "Epithelial tube formation requires Rho1-dependent actomyosin contractility to generate the cellular forces that drive...
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GPCR News
Sep 1, 20221 min read
Neuropeptide S Encodes Stimulus Salience in the Paraventricular Thalamus
September 2022 "Evaluation of stimulus salience is critical for any higher organism, as it allows for prioritizing of vital information,...
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GPCR News
Sep 1, 20221 min read
Endothelin-1 Stimulates PAI-1 Protein Expression via Dual Transactivation Pathway Dependent ROCK...
September 2022 Endothelin-1 Stimulates PAI-1 Protein Expression via Dual Transactivation Pathway Dependent ROCK and Phosphorylation of...
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GPCR News
Sep 1, 20221 min read
Lack of Oestrogen Receptor Expression in Breast Cancer Cells Does Not Correlate with Kisspeptin...
September 2022 Lack of Oestrogen Receptor Expression in Breast Cancer Cells Does Not Correlate with Kisspeptin Signalling and Migration...
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GPCR News
Sep 1, 20221 min read
Delineation of GPR15 receptor-mediated Gα protein signaling profile in recombinant mammalian cell
September 2022 "The GPR15 receptor is a G protein-coupled receptor (GPCR), which is activated by an endogenous peptide GPR15L(25-81) and...
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GPCR News
Sep 1, 20221 min read
Regulator of G Protein Signaling 20 Correlates with Long Intergenic Non-Coding RNA (lincRNAs)...
September 2022 Regulator of G Protein Signaling 20 Correlates with Long Intergenic Non-Coding RNA (lincRNAs) Harboring Oncogenic...
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GPCR News
Sep 1, 20221 min read
Microbial Metabolites Orchestrate a Distinct Multi-Tiered Regulatory Network in the Intestinal Epith
September 2022 Microbial Metabolites Orchestrate a Distinct Multi-Tiered Regulatory Network in the Intestinal Epithelium That Directs...
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GPCR News
Sep 1, 20221 min read
Pharmacological Properties and Function of PxOctβ3 Octopamine Receptor in Plutella xylostella (L.)
September 2022 "The diamondback moth (Plutella xylostella) is one of the most destructive lepidopteran pests of cruciferous vegetables,...
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GPCR News
Sep 1, 20221 min read
Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1
September 2022 "Given the promising clinical value of allosteric modulators of G protein-coupled-receptors (GPCRs), mechanistic...
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GPCR News
Sep 1, 20221 min read
Effect Delta-9-tetrahydrocannabinol and cannabidiol on milk proteins and lipid levels in HC11 cells
September 2022 "Pregnant and lactating women have been discouraged from using cannabis by Health Canada. However, the increasing rate of...
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GPCR News
Sep 1, 20221 min read
GASP1 enhances malignant phenotypes of breast cancer cells and decreases their response to...
September 2022 GASP1 enhances malignant phenotypes of breast cancer cells and decreases their response to paclitaxel by forming a vicious...
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GPCR News
Sep 1, 20221 min read
Hear the sounds: the role of G protein-coupled receptors in the cochlea
September 2022 "Sound is converted by hair cells in the cochlea into electrical signals, which are transmitted by spiral ganglion neurons...
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GPCR News
Sep 1, 20221 min read
FSH and bone: Comparison between males with central versus primary hypogonadism
September 2022 "Experimental studies proposed a direct effect of follicle-stimulating hormone (FSH) on the skeletal metabolism, but...
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