GPCR News 

September 2022 To probe the activation mechanism of the Delta opioid receptor by an agonist ADL5859 started from inactive conformation...

September 2022 "Background Cancer driver genes are usually ranked by mutation frequency, which does not necessarily reflect their driver...

September 2022 β2-Adrenergic Receptor Expression and Intracellular Signaling in B Cells Are Highly Dynamic during Collagen-Induced...

September 2022 "The bioactive lysophospholipid sphingosine-1-phosphate (S1P) acts via five different subtypes of S1P receptors (S1PRs) -...

September 2022 "The function of the actin cytoskeleton in cellular motility and trafficking has been widely studied. However,...

September 2022 Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify receptor-transducer coupling and...

September 2022 Roles of Focal Adhesion Kinase PTK2 and Integrin αIIbβ3 Signaling in Collagen- and GPVI-Dependent Thrombus Formation under...

September 2022 Cell Surface Calcium-Sensing Receptor Heterodimers: Mutant Gene Dosage Affects Ca 2+ Sensing but Not G Protein Interaction...

September 2022 Cannabinoid type-2 receptors: An emerging target for regulating schizophrenia-relevant brain circuits "Although the...

September 2022 "Melanocortin 4 receptor (MC4R) is part of the leptin-melanocortin pathway and plays an essential role in mediating energy...

September 2022 A2B Adenosine Receptor Enhances Chemoresistance of Glioblastoma Stem-Like Cells under Hypoxia: New Insights into MRP3...

September 2022 "Receptor-activity-modifying proteins (RAMPs) are ubiquitously expressed membrane proteins that associate with different G...

September 2022 High GPER expression in triple-negative breast cancer is linked to pro-metastatic pathways and predicts poor patient...

September 2022 "Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) lipids have been shown to stabilize an active conformation of class A...

September 2022 "Systemic sclerosis (SSc) is a systemic autoimmune disease with the key features of inflammation, vasculopathy and...

September 2022 "GPCR signaling and function depend on their associated proteins and subcellular locations. Besides G-proteins and...

September 2022 GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages "The...

September 2022 Computational study of the conformational ensemble of CX3C chemokine receptor 1 (CX3CR1) and its interactions with...

September 2022 Fly casting with ligand sliding and orientational selection supporting complex formation of a GPCR and a middle sized...

September 2022 Dimerization of GPCRs: Novel insight into the role of FLNA and SSAs regulating SST2 and SST5 homo- and hetero-dimer...