GPCR News 

High GPER expression in triple-negative breast cancer is linked to pro-metastatic pathways and...

Lipid Modulation of a Class B GPCR: Elucidating the Modulatory Role of PI(4,5)P 2 Lipids

A broad look into the future of systemic sclerosis

Ligands can differentially and temporally modulate GPCR interaction with 14-3-3 isoforms

GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation

Computational study of the conformational ensemble of CX3C chemokine receptor 1 (CX3CR1) and its...

Fly casting with ligand sliding and orientational selection supporting complex formation of a GPCR..

Dimerization of GPCRs: Novel insight into the role of FLNA and SSAs regulating SST2 and SST5...

Cholesterol occupies the lipid translocation pathway to block phospholipid scrambling by a GPCR

Propranolol: A “Pick and Roll” Team Player in Benign Tumors and Cancer Therapies

Integrative model of the FSH receptor reveals the structural role of the flexible hinge region

A central alarm system that gates multi-sensory innate threat cues to the amygdala

Cholesterol-Dependent Dynamics of the Serotonin 1A Receptor Utilizing Single Particle Tracking....

Angiotensin-(1-7) improves cognitive function and reduces inflammation in mice following mild trauma

Molecular insights into regulation of constitutive activity by RNA editing 5HT2C serotonin receptor

PLC-IP3-ORAI pathway participates in the activation of the MRGPRB2 receptor in mouse peritoneal...

Structural dynamics of Smoothened (SMO) in ciliary membrane and its interaction with membrane lipids

Regulation of rod photoreceptor function by farnesylated G-protein γ-subunits

Exploiting Dependence of Castration-Resistant Prostate Cancer on the Arginine Vasopressin ...

The expression and clinical significance of GPR39 in colon cancer

Phosphorylation of RGS regulates MAP kinase localization and promotes completion of cytokinesis

Primary cilia and SHH signaling impairments in human and mouse models of Parkinson’s disease

Interacting binding insights and conformational consequences of the differential activity of...

Molecular basis for variations in the sensitivity of pathogenic rhodopsin variants to 9-cis-retinal