GPCR News 

Drug Discovery Picks Up the Pace, Stays on Target

Learn more about Neurocrine Biosciences with their new video

A role for BET proteins in regulating basal, dopamine-induced and cAMP/PKA-dependent ...

Characterization of a new WHIM syndrome mutant reveals mechanistic differences in regulation of ...

Rhodopsin as a Molecular Target to Mitigate Retinitis Pigmentosa

Novel interaction between neurotrophic factor-α1/carboxypeptidase E and serotonin receptor, 5-HTR1E,

Self-docking and cross-docking simulations of G protein-coupled receptor-ligand complexes

Targeted Activation of G-Protein Coupled Receptor-Mediated Ca 2+ Signaling Drives Enhanced Cartilage

Bursicon receptor gene HLGR2 as a potential RNA interference target for control of the fall ...

Allosteric Effect of Nanobody Binding on Ligand-Specific Active States of the β2 Adrenergic Receptor

G-protein-coupled receptors as therapeutic targets for glioblastoma

Precise druggability of the PTH type 1 receptor

A Chemical Biology Toolbox Targeting the Intracellular Binding Site of CCR9: Fluorescent Ligands ...

Phospholipid Scrambling by G Protein-Coupled Receptors

Recurrent high-impact mutations at cognate structural positions in class A G protein-coupled ...

Prostaglandin signaling in ciliogenesis and development

Synaptic integration of subquantal neurotransmission by co-localized G protein coupled receptors in

Applications of Cryo-EM in small molecule and biologics drug design

HBx induces hepatocellular carcinogenesis through ARRB1-mediated autophagy to drive the G 1/S cycle

Engineered synaptic tools reveal localized cAMP signaling in synapse assembly

GPCRs Are Optimal Regulators of Complex Biological Systems and Orchestrate the Interface between ...

GPCR voltage dependence controls neuronal plasticity and behavior

Opioid Receptors and Protonation-Coupled Binding of Opioid Drugs