Blog: Blog2

GPCR News

Aug 31, 20221 min read

Novel Driver Strength Index highlights important cancer genes in TCGA PanCanAtlas patients

September 2022 "Background Cancer driver genes are usually ranked by mutation frequency, which does not necessarily reflect their driver...

Aug 31, 20221 min read

GPR108 is required for gambogic acid inhibiting NF-κB signaling in cancer

September 2022 "GPCRs are the most potential targets for drug discovery, however, their role in oncology is underappreciated and...

Jul 31, 20221 min read

MSX-122: Is an effective small molecule CXCR4 antagonist in cancer therapy?

August 2022 "Chemokines, a subgroup of cytokines along with their receptors, are involved in various biologic processes and regulation of...

Jul 31, 20221 min read

Anatomy of a partnership: Cancer Research UK teams up with Sosei Heptares

August 2022 "August 10, 2022 Cancer Research UK is working with global biopharma Sosei Heptares on a treatment they hope will bring...

Jun 30, 20221 min read

Cancer Research UK and Sosei Heptares sign agreement to advance cancer immunotherapy candidate ...

July 2022 Cancer Research UK and Sosei Heptares sign agreement to advance cancer immunotherapy candidate into clinical trials "HTL0039732...

Dec 1, 20211 min read

The development of modulators for lysophosphatidic acid receptors: A comprehensive review

Lysophosphatidic acids (LPAs) are bioactive phospholipids implicated in a wide range of cellular activities that regulate a diverse array...