GPCR News 

Coincident Regulation of PLCβ Signaling by Gq-Coupled and μOpioid Receptors Opposes Opioid- Mediated

Intermolecular Interactions in G Protein-Coupled Receptor Allosteric Sites at the Membrane Interface

Activation of GPR183 by 7 α,25-Dihydroxycholesterol Induces Behavioral Hypersensitivity through...

GB83, an Agonist of PAR2 with a Unique Mechanism of Action Distinct from Trypsin and PAR2-AP

Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5

Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1

Activation of the human chemokine receptor CX3CR1 regulated by cholesterol

Gαs and Gαq/11 protein coupling bias of two AVPR2 mutants (R68W and V162A) that cause nephrogenic di

The NPXXY Motif Regulates β-Arrestin Recruitment by the CB1 Cannabinoid Receptor

Anosmin 1 N-terminal domains modulate prokineticin receptor 2 activation by prokineticin 2

GPCR kinases generate an APH1A phosphorylation barcode to regulate amyloid-β generation

Multifunctional role of GPCR signaling in epithelial tube formation

GRK2 selectively attenuates the neutrophil NADPH-oxidase response triggered by β-arrestin recruiting