Blog: Blog2

GPCR News

Sep 30, 20221 min read

Structure of the vasopressin hormone-V2 receptor-β-arrestin1 ternary complex

October 2022 "Arrestins interact with G protein-coupled receptors (GPCRs) to stop G protein activation and to initiate key signaling...

Sep 30, 20221 min read

Mechanism of enhanced sensitivity of mutated β-adrenergic-like octopamine receptor to amitraz in...

October 2022 Mechanism of enhanced sensitivity of mutated β-adrenergic-like octopamine receptor to amitraz in honeybee Apis mellifera: An...

Jul 31, 20221 min read

GPCRs steer G i and G s selectivity via TM5-TM6 switches as revealed by structures of serotonin...

August 2022 GPCRs steer G i and G s selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors "Serotonin (or...

Jul 31, 20221 min read

Fusion protein strategies for cryo-EM study of G protein-coupled receptors

August 2022 "Single particle cryogenic-electron microscopy (cryo-EM) is used extensively to determine structures of activated G...

Jul 31, 20221 min read

Structures of β 1-adrenergic receptor in complex with Gs and ligands of different efficacies

August 2022 "G-protein-coupled receptors (GPCRs) receive signals from ligands with different efficacies, and transduce to heterotrimeric...

Jul 31, 20221 min read

Tracking receptor motions at the plasma membrane reveals distinct effects of ligands on CCR5...

August 2022 "G-protein-coupled receptors (GPCR) are present at the cell surface in different conformational and oligomeric states....

Jul 31, 20221 min read

Helix 8 in chemotactic receptors of the complement system

August 2022 "Host response to infection involves the activation of the complement system leading to the production of anaphylatoxins C3a...

Jul 31, 20221 min read

Structures of oxysterol sensor EBI2/GPR183, a key regulator of the immune response

August 2022 "Oxysterols induce the migration of B-lymphocytes and dendritic cells to interfollicular regions of lymphoid tissues through...

Jul 31, 20221 min read

Nuclear localization of histamine receptor 2 in primary human lymphatic endothelial cells

August 2022 "Histamine exerts its physiological functions through its four receptor subtypes. In this work, we report the subcellular...