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Deficiency of SCFA would lead to pro-inflammatory immune cell skewing through insufficient G-protein coupled receptor

Colorectal Cancer Published date March 11, 2023 Abstract " GPR176 belongs to the G protein-coupled receptor

My interests are in receptor theory, pharmacology applied to drug discovery and allosteric protein function

GPCR Ecosystem We bring the GPCR community to fuel GPCR drug discovery one receptor at a time.

Here, we demonstrated that the neutrophil-expressed G-protein-coupled receptor (GPCR) Mrgpra1 is a negative

Membrane-bound receptors, such as the proton-sensitive GPCR (pH-GPCR) GPR4, are considered as potential

of hepatocellular carcinoma cells in vitro Published date June 26, 2023 Abstract "G protein-coupled receptors

Here, we demonstrate that CB2, a G-protein-coupled receptor (GPCR) and member of the endocannabinoid

This established Peptidase M84 as a drug candidate for receptor mediated targeted-therapy of ovarian

Characterization of Phenotypes Associated with GPR110 Deletion Hee-Yong Kim Abstract "G-protein coupled receptor GPR110 is also highly expressed in the kidney, however, little is known about the function of this receptor

that 3BP2 has pleiotrophic function controlling bone homeostasis, immune cell function and scavenger receptor

G-protein-coupled receptor class C group 5 member D (GPRC5D), an orphan GPCR predominantly expressed

Ribas has also described a new protective role of G protein-coupled receptor kinase 2 (GRK2), a known

My interests are in receptor theory, pharmacology applied to drug discovery and allosteric protein function

Laboratory directed by Jean-Charles Schwartz in Paris, where he cloned and characterized dopamine D2 and D3 receptor

It is a specific agonist of the angiotensin II type 2 receptor.

Enhanced expression of chemokine receptor-1 (CCR1) on malignant and immunosuppressive cells modulated

subunits of G-proteins (Gα) by accelerating their GTP hydrolysis rates, which terminates G-protein coupled receptor

(RGS) protein family modulators play essential role within regulating downstream signaling of GPCR receptors

McCormick, Cristina Salmerón, Paul A Insel Tags antihistamine , cancer , gastrointestinal , histamine receptor

G-protein-coupled receptors (GPCRs) are the most intensively studied drug targets but are underexplored

In the present study, we first develop a mechanistic mathematical model of a G-protein coupled receptor

Moreover, receptor-integrin interactions were required for effective downstream signalling, leading to

Additionally, among examined G protein-coupled receptor (GPCR) genes, exposure to CPPDQ (0.01-10 μg/L

NPFF regulates a variety of physiological functions by binding to a G protein-coupled receptor (GPCR)

He completed his Ph.D. in biochemistry, studying allosteric modulation of dopamine receptors, from the

wild-type and mutant GNAS samples identified by nontargeted proteomics and involved in G protein-coupled receptor

network pharmacology and molecular docking Published date October 28, 2024 Abstract "G Protein-Coupled Receptors