Taken together, we showed that RGS20 correlates with a few HCC-associated lincRNAs harboring oncogenic

adrenergic receptor in oral squamous cell carcinoma: an emerging prognostic indicator and future therapeutic target

Our results suggest that strategies to selectively target OGR1 expression may represent a novel therapeutic

of PxOctβ3 in P. xylostella, thus, providing a theoretical basis for the design of pesticides that target

A better understanding of the underlying molecular mechanisms and the identification of treatment targets

Accordingly, from the information provided, it is plausible that specific PLC isozymes could be targeted

💡Trainees are invited to participate by presenting a trainee talk, a poster, or a pre-recorded talk

Give a talk or present a poster at the Dr. GPCR Summit 2022.

This is a great opportunity for us to come together and talk GPCRs. Do you want to be part of it?

Agreement to utilize Exscientia ’s AI-based capabilities and personalised medicine platform from target and in 2019, Sanofi in-licensed Exscientia ’s novel bispecific small molecule candidate capable of targeting two distinct targets in inflammation and immunology."

been on the rise in biotech in recent years as researchers have discovered the vast potential for GPCR-targeting drugs in treating a range of health conditions, from cancer and genetic disorders to inflammation and that star are Verily and Sosei Heptares , which have struck a research agreement to discover new GPCR targets

Ono Enters into Collaboration Agreement with Domain Therapeutics and Université de Montréal for GPCR-Targeted ; “Domain”) and Université de Montréal (Québec, Canada; “UdM”), to discover novel small molecules targeting

explore new functional chemical space and precision-engineer therapeutics with enhanced potency and tailored signaling against an undrugged GPCR target.

August 2022 "Despite the importance of members of the GPCR superfamily as targets of a broad range of Expression of GPR84 is strongly up regulated in immune cells in a range of pro-inflammatory settings

biomedical sciences with the mechanistic understanding of one of the biggest classes of pharmaceutical targets

It is a therapeutic target because it plays a role in thermogenesis, lipolysis, and bladder relaxation

DFG-funded SFB1423 and FOR2372) have joined forces to organize an international meeting, which will take The event will take place in the heart of Leipzig, which offers a colorful mixture of culture and vivid

responses to injected PTH analog peptides that are consistent with a fully functional human PTH1R in target

Therapeutic , Inc. a pre-clinical stage biotechnology company transforming the discovery of novel GPCR-targeted

it will be presenting important new data at both LSX World Congress and TIDES USA 2022 conference, taking Oliver Hartley , Orion’s Vice-President Drug Discovery, will present Orion’s novel technology for targeting describe Orion’s drug discovery platform, one of the fastest drug discovery solutions in the industry for targeting

June 2022 "G protein-coupled receptors (GPCRs) represent a major therapeutic target class as they play GPCRs respond to a wide variety of signals that range in size from photons to proteins (Foord et al., GPCRs continue to be regarded as one of the most tractable classes of drug targets and are targeted by 30%–40% of current drugs (Hauser et al., 2017), with annual sales of GPCR-targeting drugs in 2018 accounting In 2019, 5 out of 20 first-in-class approved therapeutic agents targeted GPCRs.

Sosei Heptares and Kallyope Enter Collaboration to Identify and Validate Novel Gastrointestinal GPCR Targets for Drug Discovery " Collaboration is part of Sosei Heptares ’ Target Identification and Validation Sosei Heptares compound library for its industry-leading biology platform to identify potential GPCR targets a strategic research collaboration to identify and validate novel G protein-coupled receptor (GPCR) targets

Therapeutics , a biopharmaceutical company specializing in the research and development of innovative drugs targeting

stage international biopharmaceutical company with an innovative approach to drug discovery based on targeting

These molecules are then evaluated at unprecedented speed and scale on hundreds of GPCR targets simultaneously

Dipraglurant selectively targets the metabotropic glutamate receptor subtype 5 (mGlu5) through allosteric

trial will test the pharmacokinetics and safety profile of Inversago’s lead molecule, INV-202, on a targeted

Therapeutics , a biopharmaceutical company specializing in the discovery and development of new drugs targeting Receptors (GPCRs) in immuno-oncology (IO), and Explicyte , an expert in the field of IO and innovative target The two companies will combine their expertise to identify GPCR targets and associated biomarkers to