September 2022 "Given the promising clinical value of allosteric modulators of G protein-coupled-receptors

September 2022 "Class A (rhodopsin-like) G protein-coupled receptors (GPCRs) are constitutive phospholipid

PTH-related peptide (PTHrP) bind to the parathyroid hormone receptor 1 (PTH1R) and activate the stimulatory G-protein

Biotechnology Canada Ltd, a drug discovery and development company unlocking the therapeutic potential of G

/o protein responses of some native GPCRs in neurons Beyond the Nucleus: Plastic Chemicals Activate G and Exhibition June 2 - 7, 2024 | Chemotactic Cytokines June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein

Cannabinoid CB1 Receptor Bound to a Negative Allosteric Modulator, ORG27569, and Analogs "A growing number of G-protein-coupled

Opioid receptors are G-protein-coupled receptors (GPCRs) part of cell signaling paths of direct interest

They are G-protein-coupled receptors and bind as ligand retinal, which is bound covalently to a lysine

August 2022 "Fluorescently labeled ligands are versatile molecular tools to study G protein-coupled receptors

August 2022 "G-protein-coupled receptors (GPCR) are present at the cell surface in different conformational

A major pan-receptor focus has been to identify GPCR-selective ligands that have bias in G protein-dependent

gives me great pleasure to announce the fourth hybrid symposium on regulatory autoantibodies targeting G-protein-coupled

Gáspár Pándy-Szekeres ) will present and demonstrate the newest resources of the GPCRdb: 1) the new G

Enabling the Design of Nucleoside Functional Switches for the A2A Adenosine Receptor "Modulators of the G

regulation of gluconeogenic gene transcription is endocytosis-dependent in primary hepatocytes "A number of G

Here, we discovered that the epithelial-cell-derived antimicrobial peptides defensins activated orphan G-protein-coupled

meningitidis and identified 30 N-acyl amides with representative members serving as agonists of the G-protein

October 2022 "The very large G protein-coupled receptor (VLGR1, ADGRV1) is the largest member of the

recruitment, activation, and scaffolding of numerous cytoplasmic signaling complexes and assist in G-protein

coupling to the same GPCR in living cells "β-arrestins mediate regulatory processes for over 800 different G

These disorders are mainly related to the abnormalities in the rod G protein-coupled receptor (GPCR),

high-throughput drug screening, drug efficacy analyses, and toxicity studies; technologies that stabilize G

Many G-protein-coupled receptors (GPCRs) including EP4 are localized in cilia for modulating cAMP signaling

Receptor-activity-modifying proteins (RAMPs) are ubiquitously expressed membrane proteins that associate with different G

4,5-bisphosphate (PI(4,5)P2) lipids have been shown to stabilize an active conformation of class A G-protein

Besides G-proteins and β-arrestins, 14-3-3 proteins participate in GPCR trafficking and signaling, and

antagonist and agonist ligands "The CX3C chemokine receptor 1 (CX3CR1), a member of the class A of G

June 2022 "G protein-coupled receptors (GPCRs) represent a major therapeutic target class as they play