Search Results
266 items found for "drug repurposing"
- Feeder or trigger – CCR2 as a scavenger and regulator of cell migration
What are the implications in drug discovery?
- Dr. Rosie Dawaliby Podcast!
🥁 Drum rolls, please! Our guest is the wonderful Dr. Rosie Dawaliby!
- Ode to GPCRs
, Sir James Whyte Black, and Gertrude Belle Elion for their discoveries of important principles for drug treatment.[24–30] Black was particularly interested in developing drugs that targeted GPCRs and was
- Exploiting Dependence of Castration-Resistant Prostate Cancer on the Arginine Vasopressin ...
Exploiting Dependence of Castration-Resistant Prostate Cancer on the Arginine Vasopressin Signaling Axis by Repurposing
- Residency time of agonists does not affect the stability of GPCR-arrestin complexes
September 2022 " Background and purpose: The interaction of arrestins with G-protein coupled receptors
- The integrin ligand SVEP1 regulates GPCR-mediated vasoconstriction via integrins α9β1 and α4β1
August 2022 " Background and purpose: Vascular tone is regulated by the relative contractile state of
- Research Network on Signal Transduction (ERNEST) has established an Emergency Fund for Ukrainian ...
The purpose of the STSM is to carry out a collaborative research project on topics relevant to the network
- N-terminal alterations turn the gut hormone GLP-2 into an antagonist with gradual loss of GLP-2 ...
gradual loss of GLP-2 receptor selectivity towards more GLP-1 receptor interaction "Background and purpose
- Expression pattern and clinical significance of beta 2-adrenergic receptor in oral squamous cell...
receptor in oral squamous cell carcinoma: an emerging prognostic indicator and future therapeutic target " Purpose
- Reversible Photocontrol of Dopaminergic Transmission in Wild-Type Animals
opens the way to remotely controlling dopaminergic neurotransmission for fundamental and therapeutic purposes
- Design and validation of recombinant protein standards for quantitative Western blot analysis of...
This renders full-length recombinant GPCRs useless for analytical purposes, a problem that can be overcome
- A new Kunitz-type snake toxin family associated with an original mode of interaction with the...
associated with an original mode of interaction with the vasopressin 2 receptor "Abstract Background and purpose
- Endothelin-1 Stimulates PAI-1 Protein Expression via Dual Transactivation Pathway Dependent ROCK...
The purpose of this study was to evaluate the role of dual transactivation of EGF and TGF-β receptors
- Exendin-4 Attenuates Remodeling in the Remote Myocardium of Rats After an Acute Myocardial ...
Activating β-Arrestin-2, Protein Phosphatase 2A, and Glycogen Synthase Kinase-3 and Inhibiting β-Catenin Purpose