Search Results
494 items found for "Bcl-2"
- GPR15 expressed in T lymphocytes from RA patients is involved in leukocyte chemotaxis to the...
October 2022 GPR15 expressed in T lymphocytes from RA patients is involved in leukocyte chemotaxis to
- Case Report of a Juvenile Patient with Autism Spectrum Disorder with a Novel Combination of Copy...
October 2022 Case Report of a Juvenile Patient with Autism Spectrum Disorder with a Novel Combination hybridization (array-CGH), we identified two CNVs, both triplex duplications of 324 kb on 3p26.3, and 284
- Identification of A2BAR as a potential target in colorectal cancer using novel fluorescent GPCR...
October 2022 Identification of A2BAR as a potential target in colorectal cancer using novel fluorescent We selected the adenosine receptor 2B (A2BAR), specifically expressed in cancer cell lines compared with
- Increased Anxiety-like Behaviors in Adgra1-/- Male But Not Female Mice are Attributable to...
October 2022 Increased Anxiety-like Behaviors in Adgra1-/- Male But Not Female Mice are Attributable
- Intermolecular Interactions in G Protein-Coupled Receptor Allosteric Sites at the Membrane Interface
October 2022 Intermolecular Interactions in G Protein-Coupled Receptor Allosteric Sites at the Membrane
- Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling
October 2022 "Adhesion G protein-coupled receptors (aGPCRs) are keys of many physiological events and
- Endogenous ligand recognition and structural transition of a human PTH receptor
October 2022 "Endogenous parathyroid hormone (PTH) and PTH-related peptide (PTHrP) bind to the parathyroid structures of six forms of the human PTH1R-Gs complex in the presence of PTH or PTHrP at resolutions of 2.8
- Discovery and In Vivo Evaluation of ACT-660602: A Potent and Selective Antagonist of the Chemokine..
October 2022 Discovery and In Vivo Evaluation of ACT-660602: A Potent and Selective Antagonist of the
- Structural view of G protein-coupled receptor signaling in the retinal rod outer segment
October 2022 "Visual phototransduction is the most extensively studied G protein-coupled receptor (GPCR
- Endosomal parathyroid hormone receptor signaling
October 2022 "The canonical model for G protein-coupled receptors (GPCRs) activation assumes that stimulation
- Nanobodies as Probes and Modulators of Cardiovascular G Protein-Coupled Receptors
October 2022 "Understanding the activation of G protein-coupled receptors (GPCRs) is of paramount importance
- High hedgehog signaling is transduced by a multikinase-dependent switch controlling the...
October 2022 High hedgehog signaling is transduced by a multikinase-dependent switch controlling the
- Reversible Photocontrol of Dopaminergic Transmission in Wild-Type Animals
October 2022 "Understanding the dopaminergic system is a priority in neurobiology and neuropharmacology
- Structural perspectives on the mechanism of signal activation, ligand selectivity and allosteric...
October 2022 Structural perspectives on the mechanism of signal activation, ligand selectivity and allosteric
- Mechanistic basis of GPCR activation explored by ensemble refinement of crystallographic structures
October 2022 "G protein-coupled receptors (GPCRs) are important drug targets characterized by a canonical
- Structure of the vasopressin hormone-V2 receptor-β-arrestin1 ternary complex
October 2022 "Arrestins interact with G protein-coupled receptors (GPCRs) to stop G protein activation
- Recurrent hypoglycemia increases hepatic gluconeogenesis without affecting glycogen metabolism or sy
October 2022 Recurrent hypoglycemia increases hepatic gluconeogenesis without affecting glycogen metabolism
- ADGRL3 genomic variation implicated in neurogenesis and ADHD links functional effects to the...
October 2022 ADGRL3 genomic variation implicated in neurogenesis and ADHD links functional effects to
- Allosteric modulation of GPCRs: From structural insights to in silico drug discovery
October 2022 "G protein-coupled receptors (GPCRs) play critical roles in human physiology and are one
- Dr. GPCR Virtual Cafe - Postponed
GPCR Virtual Cafe with Matthew Eddy scheduled for tomorrow (Sep 29th, 2022) due to Hurricane Ian that
- TRPM3 in the eye and in the nervous system - from new findings to novel mechanisms
August 2022 "The calcium-permeable cation channel TRPM3 can be activated by heat and the endogenous steroid In addition, a micro-RNA gene (miR-204) is located within the TRPM3 gene.
- Community guidelines for GPCR ligand bias: IUPHAR review 32
August 2022 "GPCRs modulate a plethora of physiological processes and mediate the effects of one-third
- Molecular insights into psychedelic drug action
August 2022 "A confluence of factors has renewed interest in the scientific understanding and translational
- Molecular targets of psychedelic-induced plasticity
August 2022 "Psychedelic research across different disciplines and biological levels is growing at a
- AlphaFold2 versus experimental structures: evaluation on G protein-coupled receptors
August 2022 "As important drug targets, G protein-coupled receptors (GPCRs) play pivotal roles in a wide
- Adenosine receptor signalling in Alzheimer's disease
August 2022 "Alzheimer's disease (AD) is the most common dementia in the elderly and its increasing prevalence
- GRK2 in cardiovascular disease and its potential as a therapeutic target
August 2022 "Cardiovascular diseases (CVDs) represent the leading cause of death globally.
- Posttranslational modifications in GPCR internalization
August 2022 "G protein-coupled receptors (GPCRs) are the largest family of membrane receptors that serve