Search Results
292 items found for "Molecular diversity"
- Engineered synaptic tools reveal localized cAMP signaling in synapse assembly
Here, we describe new tools, referred to as "SynTAMs" for synaptic targeting molecules, that enable localized
- Focusing on the role of secretin/adhesion (Class B) G protein-coupled receptors in placental...
largest family of membrane proteins in eukaryotes and the largest drug target family to date, exhibit diversity
- Integration and Spatial Organization of Signaling by G Protein-Coupled Receptor Homo- and ...
essential in biology and understanding how cells integrate signals from a variety of information-coding molecules
- The development of modulators for lysophosphatidic acid receptors: A comprehensive review
LPAs) are bioactive phospholipids implicated in a wide range of cellular activities that regulate a diverse
- β-arrestin1 promotes tauopathy by transducing GPCR signaling, disrupting microtubules and autophagy
However, it is unclear how diverse GPCRs similarly affect Aβ and tau pathogenesis.
- β2-Adrenergic Receptor Expression and Intracellular Signaling in B Cells Are Highly Dynamic during..
Adrenergic receptors on B cells and intracellular β2-ADR downstream molecules (G protein-coupled receptor
- Lack of Oestrogen Receptor Expression in Breast Cancer Cells Does Not Correlate with Kisspeptin...
is not universally true that kisspeptin/KISS1R stimulate migration or pro-metastatic behaviour, as divergent Whether this divergence is related to the observed differences in β-arrestin complements warrants further
- Class B1 GPCR Dimerization: Unveiling Its Role in Receptor Function and Signaling
peptide-1 receptor dimerization differentially regulates agonist signaling but does not affect small molecule
- Actions of Parathyroid Hormone Ligand Analogues in Humanized PTH1R Knockin Mice
Divergence, however, in the amino acid sequences of rodent and human PTH receptors (rat and mouse PTH1Rs
- Exendin-4 Attenuates Remodeling in the Remote Myocardium of Rats After an Acute Myocardial ...
Administration of Exendin-4 to MI rats reduced the infarct size and reversed the aforementioned signaling molecules
- Illuminating GPCR Research: FRET and BRET-Based Sensors Shed Light on Cellular Signaling
operate on the principle of energy transfer between a fluorescent or luminescent donor and acceptor molecules
- Regulators of G-protein signaling: essential players in GPCR signaling
proteins has been implicated in a range of diseases, and understanding the mechanisms of these complex molecules