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452 items found for "Stefano Moro"
- OMass Therapeutics's founder, Carol Robinson, has been awarded the prestigious Louis-Jeantet ...
#DrugDiscovery #MassSpec #Award #massspectrometry" Read more at the source #DrGPCR #GPCR #IndustryNews
- Case Report of a Juvenile Patient with Autism Spectrum Disorder with a Novel Combination of Copy...
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- Pepducin-mediated G Protein-Coupled Receptor Signaling in the Cardiovascular System
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- 📰 GPCR Weekly News, June 5 to 11, 2023
GPCR Binders, Drugs, and more Adenosine A2A Receptor (A2AAR) Ligand Screening Using the 19F-NMR Probe Reviews, GPCRs, and more Diversification processes of teleost intron-less opsin genes.
- Coincident Regulation of PLCβ Signaling by Gq-Coupled and μOpioid Receptors Opposes Opioid- Mediated
The primary analgesic target of opioids is the μ-opioid receptor (MOR). Here we investigated a potential mechanism for regulation of PLC signaling downstream of MOR in HEK293 cells and found that MOR alone could not stimulate PLC, but rather required a coincident signal from regulators, Gβγ or Gq, ex vivo in periaqueductal gray (PAG) slices increased the potency of the selective MOR of opioid analgesics. " Read more at the source #DrGPCR #GPCR #IndustryNews Subscribe to the Newsletter
- TRPM3 in the eye and in the nervous system - from new findings to novel mechanisms
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- Deciphering the signaling mechanisms of β-arrestin1 and β-arrestin2 in regulation of cancer cell...
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- In vivo detection of GPCR-dependent signaling using fiber photometry and FRET-based biosensors
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- Conservation of Allosteric Ligand Binding Sites in G-Protein Coupled Receptors
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- Sosei Heptares and Kallyope Enter Collaboration to Identify and Validate Novel Gastrointestinal GPCR
with a goal of creating new drug discovery programs in the area of gastrointestinal diseases. " Read more
- 📰 GPCR Weekly News, February 13 to 19, 2023
GPCR Binders, Drugs, and more Novel targets for potential therapeutic use in Diabetes mellitus. Reviews, GPCRs, and more Single nucleotide variations encoding missense mutations in G protein-coupled
- CCL25/CCR9 interaction promotes the malignant behavior of salivary adenoid cystic carcinoma via...
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- Cholesterol-Dependent Dynamics of the Serotonin 1A Receptor Utilizing Single Particle Tracking....
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- Structural basis for receptor selectivity and inverse agonism in S1P5 receptors
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- GPCR kinase phosphorylation of distal C-tail sites specifies βarrestin1-mediated signaling by...
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- The Bile Acid Membrane Receptor TGR5 in Cancer: Friend or Foe?
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- Divergent roles for the gut intraepithelial lymphocyte GLP-1R in control of metabolism, microbiota..
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- Addex Raises $10 Million In Equity Financing
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- 📰 GPCR Weekly News, July 24 to July 30, 2023
Submit a 1-minute abstract video and tell us more about your project using this form. GPCR Binders, Drugs, and more Development of a V5-tag-directed nanobody and its implementation as an
- Neurocrine Biosciences Announces Positive Phase 3 Data for KINECT-HD Study Evaluating Valbenazine...
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- Confo Therapeutics Doses First Subjects In Phase 1 Clinical Trial Of CFTX-1554 For The Treatment ...
safety, tolerability and pharmacokinetics of CFTX-1554 in healthy subjects (NCT05260658). " Read more
- Perkins’ Head of Molecular Endocrinology and Pharmacology, Professor Kevin Pfleger, was appointed...
next year, in collaboration with the Australasian Pharmaceutical Science Association ( APSA ).” " Read more
- First in Human: Early-stage COVID therapies hold promise against omicron variant
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- ADGRL3 genomic variation implicated in neurogenesis and ADHD links functional effects to the...
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- Novel Therapies for Cardiometabolic Disease: Recent Findings in Studies with Hormone...
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- GB83, an Agonist of PAR2 with a Unique Mechanism of Action Distinct from Trypsin and PAR2-AP
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- Mechanistic Understanding of the Palmitoylation of Go Protein in the Allosteric Regulation of...
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- Cholesterol-Dependent Dynamics of the Serotonin1A Receptor Utilizing Single Particle Tracking: ...
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