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Authors Judith Anthea Stolwijk , Susanne Wallner , Judith Heider , Bernadett Kurz , Lisa Pütz , Stefanie Michaelis , Barbara Goricnik , Julia Erl , Linda Frank , Mark Berneburg , Frank Haubner , Joachim Wegener

Likely, many other metabolites will be present at high concentrations. helps explain how the gut microbiome may be affecting peripheral immune cells, and consequently Western lifestyle Authors Quanbo Wang , Charles R Mackay Tags Gut microbiota , Western lifestyle diseases , portal vein

Pathways linked to these tumor suppressor proteins may enhance immune surveillance, prevent carcinogenesis

Notably, GPR132 activation by 8GL promoted differentiation and reduced colony formation in human AML cell lines Jiacheng He, Dan Huang, Yumiao Zhao, Chan Zhang, Xiyun Ye, Ying Huang, Ruth Nussinov, Junke Zheng, Mingyao Liu

Here, we show that HRH1 is widely expressed in various cancer cell lines and cancer tissues and that

Kathleen Caron on the web UNC-Chapel Hill Department of Cell Biology and Physiology UNC Lineberger Comprehensive

As therapeutic options are limited, novel targets, and agents for therapeutic intervention are urgently

survival of terminally differentiated CD8+ T cells Cheng-Chih Hsiao Adhesion GPCR GPR116/Adgrf5 controls a lineage Neuroscience; 2022 - present: Researcher associate, Netherlands Brain Bank" Cheng-Chih Hsiao on the web LinkedIn ReseachGate Adhesion GPCR GPR116/Adgrf5 controls a lineage of anti-thermogenic adipocytes with implications

(EAPC) with 95 % confidence intervals (95 % CI) fitted age-period-cohort (APC) models to assess non-linear

Exposure to CPPDQ (0.01-10 μg/L) further decreased expressions of daf-7 encoding TGF-β ligand, jnk-1 Authors Xin Wan, Geyu Liang, Dayong Wang Tags Accumulation , C. elegans , CPPDQ , Neurotoxicity Source

Mihaylov Intricacies Of Complex Assembly And Ligand Interaction In The Adhesion GPCR Latrophilin/Cirl Mihaylov on the web Crick LinkedIn X (Twitter) Google Scholar Intricacies Of Complex Assembly And Ligand

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function in human non-ischaemic heart failure Published date April 1, 2023 Abstract " Aims: A causal link

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Signaling Profile of Adhesion GPCR ADGRL1 / Latrophilin-1 Sheila Ribalta-Mena GPR110 modulates anxiety-like Notably, our pilot data from luminal-type breast cancer cell lines representative of breast carcinomas To test this hypothesis, we created WNT-like MB cell lines stably expressing tet-on wild-type BAI3 or Ligand binding and mechanical force applied on the ECR regulate receptor function. Mariam Melkumyan on the web LinkedIn Google Scholar < Previous Session Next Session >

dysfunction and immunotherapy failure in mice Published date July 15, 2023 No Abstract available No Authors listed

, 2022 Abstract The complement fragment C5a is one of the most potent proinflammatory glycoproteins liberated C5a is established to interact with a set of genomically related transmembrane receptors, like C5aR1 structure of C5aR2 and its interaction specificity toward C5a is not structurally elucidated in the literature Authors Aurosikha Das, Pulkit K Gupta, Soumendra Rana Tags C5a; C5aR2/C5L2 receptor; lipid bilayer; molecular

have developed antibody-drug conjugates (ADCs) targeting CD97, by screening a synthetic human antibody library We initially tested the ADC using in vitro WST-8 viability assays in human GBM cell lines and cell types Dimitris Placantonakis on the web Placantonakis Lab Google Scholar LinkedIn Adhesion G protein-coupled Nicole Perry-Hauser on the web LinkedIn Research Gate Pubmed Dr.

hypoxia on migration, proliferation, invasion, and signaling in 2D and 3D models of breast cancer cell lines There were some discrepancies in the responses of each cell line to the isoform-specific antagonists

Michel Bouvier on the web Wikipedia IRIC Bouvier Lab Google Scholar Pubmed ResearchGate Twitter LinkedIn

Prenyltransferases tether isoprenoid lipids to proteins via a thioether linkage during prenylation. Pharmacological inhibition of the lipid synthesis pathway by statins is a therapeutic approach to control monitored the subcellular localization of fluorescently tagged Gγ subunits and their mutants using live-cell

Authors Ze Wu , Qiongqiong Jia , Boqun Liu , Lanlan Fang , Peter C K Leung , Jung-Chien Cheng Tags Invasion

form multimeric complexes with other GPCRs and characterized the relative size of the complexes in a live-cell PIE-FCCS can resolve membrane protein density, diffusion, and multimerization state in live cells at We probed CXCR4 and β2AR homo- and heteromultimerization in model cell lines and found that CXCR4 assembles CXCR4 multimers in MDA-MB-231 and HCC4006 cells to a higher degree than in COS-7 and CHO cells and in a ligand-dependent Authors Junyi Liang , Mohamed Seghiri , Pradeep Kumar Singh , Hyeon Gyu Seo , Ji Yeong Lee , Yoonjung

therapeutic strategy. " Victoria Rasmussen on the web Tri-Institutional PhD Program Chemical Biology LinkedIn

The lung cancer cell line H1299-BRS3 was treated with MK-5046, an agonist of BRS3, for different durations

Lysophosphatidic acid (LPA) is a lipid that activates G protein-coupled receptors (GPCRs), enhancing group previously reported that LPA induces production of CCN1 protein in human prostate cancer cell lines There are multiple examples of the induction of CCN proteins by LPA, and by the related lipid mediator

, BP , Beta chain , Bovine adrenal medulla peptide 8-22 , Bullous pemphigoid , C-C motif chemokine ligand volume in 1 second from baseline , Prurigo nodularis , SP , STAT , Sialic-acid-binding immunoglobulin-like