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304 items found for "cell-cell communication"
- 📰 GPCR Weekly News - January 9 to 15, 2023
collaborations GPCR Therapeutics Announces Launch of US Phase 2 Trial of GPC-100 in Multiple Myeloma Call
- 📰 GPCR Weekly News, February 6 to 12, 2023
Listing Rule 5635(c)(4) arcoscreen is one of the 13 biotech companies to discover in western in 2023 Call
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🌐 🤝 We want to bring closer the #GPCR community! Join the Dr.
- 📰 GPCR Weekly News, February 5 to 11, 2024
have a poster session in breakout rooms on Zoom; if you are interested in sharing your work with our community You'll share your contributor articles with the community, stay updated with GPCR literature, network
- Mechanistic Understanding of the Palmitoylation of Go Protein in the Allosteric Regulation of...
Furthermore, the community network analysis suggests that the palmitoylation of Go not only allosterically
- SLAS2022 International Conference and Exhibition
any changes made that will impact our ability to hold the event in-person, we will notify the SLAS community
- TeachOpenCADD - A teaching platform for computer-aided drug design
Since we cover both the theoretical as well as practical aspect of these topics, the platform addresses students and researchers with a biological/chemical as well as a computational background. Topics are continuously expanded and open for contributions from the community.
- GPCRS: AN ODYSSEY FROM STRUCTURE, SIGNALING AND REGULATION TO THERAPEUTICS
While GPCRs are considered a well-established field, recent technological advances to dissect the molecular This timely meeting will not only provide an inclusive forum for communication, but also a platform for
- 📰 GPCR Weekly News, March 18 to 24, 2024
If you want to showcase your research, you can submit a poster presentation to our community, take advantage
- Allosteric Effect of Nanobody Binding on Ligand-Specific Active States of the β2 Adrenergic Receptor
Dynamic network analysis further reveals that Nb80 binding triggers tighter and stronger local communication ligand-binding sites, primarily involving residues around ICL2 and the intracellular end of TM3, TM5, TM6, as well
- 📰 GPCR Weekly News, April 22 to 28, 2024
Submit a few slides for a poster presentation to showcase your research and network with our community
- ADGRL3 genomic variation implicated in neurogenesis and ADHD links functional effects to the...
effects to the incretin polypeptide GIP "Attention deficit/hyperactivity disorder (ADHD) is the most common Docking analysis of rs35106420, harbored in the ADGLR3-hormone receptor domain (HRM, a common extracellular
- The expression and clinical significance of GPR39 in colon cancer
September 2022 " Background: Colorectal cancer is the third most common cancer and requires more prognostic
- Adenosine receptor signalling in Alzheimer's disease
October 2022 "Alzheimer's disease (AD) is the most common dementia in the elderly and its increasing
- Adenosine receptor signalling in Alzheimer's disease
August 2022 "Alzheimer's disease (AD) is the most common dementia in the elderly and its increasing prevalence
- Identification of hub genes in the subacute spinal cord injury in rats
September 2022 "Background Spinal cord injury (SCI) is a common trauma in clinical practices.
- GPCRs steer G i and G s selectivity via TM5-TM6 switches as revealed by structures of serotonin...
Together, these results present a common mechanism of Gs versus Gi protein coupling selectivity or promiscuity
- G-protein-coupled receptors as therapeutic targets for glioblastoma
Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumour in adults.
- GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for...
Herein, we demonstrate that a thiophene modification at the C8 position in the common adenine scaffold
- Successful prednisolone or calcimimetic treatment of acquired hypocalciuric hypercalcemia caused...
Our observations with these prominent commonalities may provide new insights into the phenotype and characteristics
- Combined docking and machine learning identify key molecular determinants of ligand pharmacological
We hypothesized that there is a common set of receptor interactions made by ligands of diverse structures
- β-arrestin1 promotes tauopathy by transducing GPCR signaling, disrupting microtubules and autophagy
GPCRs share a common mechanism of action via the β-arrestin scaffolding signaling complexes, which not
- Odorant G protein-coupled receptors as potential therapeutic targets for adult diffuse gliomas ...
Glioma is the most common adult malignant brain tumor and requires novel therapeutic strategies to improve
- Recurrent high-impact mutations at cognate structural positions in class A G protein-coupled ...
They have a common structure and, signaling through a much smaller set of G proteins, arrestins, and