This study demonstrates that GPR37, a GPCR receptor, is highly expressed in CRC. Further tests showed that GPR37 protects cancer cells from ferroptosis by upregulating SCD1 expression

Ljubljana, Slovenia, and at the University of Bonn, Germany, working initially on the role of prostaglandin receptor

EVs express prosaposin, which binds to macrophage GPR37 to increase expression of the efferocytosis receptor

his Ph.D. in Neuroscience from Ohio State University focusing on synaptic plasticity and adrenergic receptor

Membrane-bound receptors, such as the proton-sensitive GPCR (pH-GPCR) GPR4, are considered as potential

< GPCR News < GPCRs in Oncology and Immunology Metallo-protease Peptidase M84 from Bacillusaltitudinis Abstract "We have purified Peptidase M84 from Bacillus altitudinis in an effort to isolate anticancer proteases This metallo-protease had no discernible impact on normal cell survival, but it specifically induced This established Peptidase M84 as a drug candidate for receptor mediated targeted-therapy of ovarian

GPCR Ecosystem We bring the GPCR community to fuel GPCR drug discovery one receptor at a time.

Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Welcome Reception

recruiting and regulating tumor-associated macrophages Published date May 28, 2023 Abstract "Adenosine 2a receptor

disease model to study EBV-induced lymphomagenesis, incorporating genomic, transcriptomic, and in-depth proteomic Enhanced expression of chemokine receptor-1 (CCR1) on malignant and immunosuppressive cells modulated

Laboratory directed by Jean-Charles Schwartz in Paris, where he cloned and characterized dopamine D2 and D3 receptor

He completed his Ph.D. in biochemistry, studying allosteric modulation of dopamine receptors, from the

Receptor data shows how GPCR control of cellular function goes far beyond simple second messenger production

Infections are an important complication after B-cell maturation antigen (BCMA)-directed chimeric antigen receptor

, single-center analysis we evaluated infectious complications after BCMA-targeted chimeric-antigen-receptor

Much of this work centered on elucidating novel mechanisms by which β-adrenergic receptors impact cardiac

also shared their admiration for the work of a mutual friend and discussed the history of muscarinic receptors Lastly, they discussed the progress of new drugs targeting specific receptors for various diseases, with challenges within universities, including resistance to change and the need to communicate expectations and protect

also shared their admiration for the work of a mutual friend and discussed the history of muscarinic receptors Lastly, they discussed the progress of new drugs targeting specific receptors for various diseases, with challenges within universities, including resistance to change and the need to communicate expectations and protect

Neitzel , Jessica Cornell , Samantha Rea , Ian Mills , Maya S Silver , Jovanni D Ahmad , Konstantin G

Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Leave for dinner reception

CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Complimentary Reception

< GPCR News < GPCRs in Oncology and Immunology S1P Signaling Genes as Prominent Drivers of BCR-ABL1-Independent