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362 items found for "Vivian G Oehler"
- Design and validation of recombinant protein standards for quantitative Western blot analysis of...
radioligand binding assays with antibody-antigen interaction-based approaches for quantitative analysis of G
- GRK2 in cardiovascular disease and its potential as a therapeutic target
G protein-coupled receptors (GPCRs) are critical myocardial signal transducers which regulate cardiac
- Luciferase-based GloSensor™ cAMP assay: Temperature optimization and application to cell-based kinet
Luciferase-based GloSensor™ cAMP assay: Temperature optimization and application to cell-based kinetic studies "G
- HDX-MS-optimized approach to characterize nanobodies as tools for biochemical and structural ...
critical component in multiple immune signaling processes and is dependent on activation by Ras and G
- TLR4 biased small molecule modulators
Currently, attention was mainly paid to biased signaling modulators targeting G protein-coupled receptors
- A Model for the Signal Initiation Complex Between Arrestin-3 and the Src Family Kinase Fgr
Arrestins regulate a wide range of signaling events, most notably when bound to active G protein-coupled
- Allosteric ligands control the activation of a class C GPCR heterodimer by acting at the transmembra
G protein-coupled receptors (GPCRs) are among the most promising drug targets.
- The development of modulators for lysophosphatidic acid receptors: A comprehensive review
They recognize two types of G protein-coupled receptors (LPARs): LPA1-3 receptors and LPA4-6 receptors
- PH-Binding Motif in PAR4 Oncogene: From Molecular Mechanism to Drug Design
October 2022 "While the role of G-protein-coupled receptors (GPCR) in cancer is acknowledged, their underlying
- Genome-scale CRISPR screening reveals that C3aR signaling is critical for rapid capture of fungi...
The highest scoring protective hits included the complement C3a receptor (C3aR), a G-protein coupled
- GPR15 expressed in T lymphocytes from RA patients is involved in leukocyte chemotaxis to the...
GPR15 is a G protein-coupled receptor (GPCR) located on chromosome 3 and has similarity in its sequence
- GPR3 expression in retinal ganglion cells contributes to neuron survival and accelerates axonal...
G protein-coupled receptor 3 (GPR3) belongs to the class A rhodopsin-type GPCR family and is highly expressed
- In Vitro and In Silico Characterization of Kurarinone as a Dopamine D 1A Receptor Antagonist and ...
Alterations in the expression and/or activity of brain G-protein-coupled receptors (GPCRs) such as dopamine
- β-arrestin1 promotes tauopathy by transducing GPCR signaling, disrupting microtubules and autophagy
G protein-coupled receptors (GPCRs) have been shown to play integral roles in Alzheimer's disease pathogenesis
- On-cell nuclear magnetic resonance spectroscopy to probe cell surface interactions
on-cell NMR spectroscopy to characterize ligand interactions with cell surface membrane proteins such as G-protein
- High GPER expression in triple-negative breast cancer is linked to pro-metastatic pathways and...
considered that TNBC is an estrogen-independent breast cancer, while a new estrogen receptor, namely G
- GASP1 enhances malignant phenotypes of breast cancer cells and decreases their response to...
forming a vicious cycle with IGF1/IGF1R signaling pathway "There is a potential correlation between G-protein-coupled
- Biased GPCR signaling by the native parathyroid hormone-related protein 1 to 141 relative to its...
amino acids, our current understanding on how endogenous PTHrP transduces signals through its cognate G-protein
- GPR125 (ADGRA3) is an autocleavable adhesion GPCR that traffics with Dlg1 to the basolateral...
Dlg1 to the basolateral membrane and regulates epithelial apicobasal polarity "The adhesion family of G
- GPCRS: AN ODYSSEY FROM STRUCTURE, SIGNALING AND REGULATION TO THERAPEUTICS
APRIL 06 - 09, 2022 | | SNOWBIRD RESORT, UTAH, UNITED STATES The superfamily of G protein-coupled receptors
- Functional Characterization of the Venus Flytrap Domain of the Human TAS1R2 Sweet Taste Receptor
September 2022 "The human sweet taste receptor is a heterodimeric receptor composed of two distinct G-protein-coupled
- Endothelin-1 Stimulates PAI-1 Protein Expression via Dual Transactivation Pathway Dependent ROCK...
In addition, as an intermediary of G protein-coupled receptor (GPCR) signaling, the functions of ROCK
- GPCR/endocytosis/ERK signaling/S2R is involved in the regulation of the internalization...
We investigated the influence of specific inhibitors of G protein-coupled receptors (GPCR), endocytosis
- Unlocking the Therapeutic Potential of Previously Undruggable GPCRs
Executive Summary This whitepaper will provide an overview of G Protein-Coupled Receptors (GPCRs) and intracellular face of the receptor, leading to the binding and activation of cytosolic effector proteins: the G proteins after which GPCRs are named, and arrestins which both shut off G protein activity and elicit G protein-independent signaling pathways. agonists with different levels of signaling activity, biased agonists that preferentially activate either G
- Novel interaction between neurotrophic factor-α1/carboxypeptidase E and serotonin receptor, 5-HTR1E,
involving interaction between neurotrophic factor-α1 (NF-α1/carboxypeptidase E, CPE) and human 5-HTR1E, a G
- Bursicon receptor gene HLGR2 as a potential RNA interference target for control of the fall ...
potential RNA interference target for control of the fall webworm Hyphantria cunea Background: Insect G
- Melatonin MT 2 receptor is expressed and potentiates contraction in human airway smooth muscle
Numerous physiological effects of melatonin are mediated via its specific G protein-coupled receptors
- Involvement of various chemokine/chemokine receptor axes in trafficking and oriented locomotion ...
molecular weight proteins that their functional activities are achieved by binding to the cell surface G