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September 2022 "Class A (rhodopsin-like) G protein-coupled receptors (GPCRs) are constitutive phospholipid We considered whether cholesterol, a prominent component of the plasma membrane, limits the ability of

PTH-related peptide (PTHrP) bind to the parathyroid hormone receptor 1 (PTH1R) and activate the stimulatory G-protein

remains unknown, and there is no ideal drug for the specific treatment of pSS. β-arrestin2 is a key protein that mediates desensitization and internalization of G protein-coupled receptors (GPCRs) and it participates

Biotechnology Canada Ltd, a drug discovery and development company unlocking the therapeutic potential of G Protein-Coupled

CB1 Receptor Bound to a Negative Allosteric Modulator, ORG27569, and Analogs "A growing number of G-protein-coupled

They are G-protein-coupled receptors and bind as ligand retinal, which is bound covalently to a lysine

August 2022 "Fluorescently labeled ligands are versatile molecular tools to study G protein-coupled receptors

August 2022 "G-protein-coupled receptors (GPCR) are present at the cell surface in different conformational

A major pan-receptor focus has been to identify GPCR-selective ligands that have bias in G protein-dependent

me great pleasure to announce the fourth hybrid symposium on regulatory autoantibodies targeting G-protein-coupled

Pharmacology - The Hauser Group Postdoctoral Scholar – iPSC in cardiac and endothelial cell function Protein GPCR Function AlphaFold3 versus experimental structures: assessment of the accuracy in ligand-bound G protein-coupled

Enabling the Design of Nucleoside Functional Switches for the A2A Adenosine Receptor "Modulators of the G protein-coupled

of gluconeogenic gene transcription is endocytosis-dependent in primary hepatocytes "A number of G protein-coupled

we discovered that the epithelial-cell-derived antimicrobial peptides defensins activated orphan G-protein-coupled

meningitidis and identified 30 N-acyl amides with representative members serving as agonists of the G-protein

to the same GPCR in living cells "β-arrestins mediate regulatory processes for over 800 different G protein-coupled

Gáspár Pándy-Szekeres ) will present and demonstrate the newest resources of the GPCRdb: 1) the new G protein

These disorders are mainly related to the abnormalities in the rod G protein-coupled receptor (GPCR),

4,5-bisphosphate (PI(4,5)P2) lipids have been shown to stabilize an active conformation of class A G-protein

antagonist and agonist ligands "The CX3C chemokine receptor 1 (CX3CR1), a member of the class A of G Protein-Coupled

acid derivatives as a new class of GPR34 antagonists Larixol is not an inhibitor of Gαi containing G proteins Immunology Context-dependent ciliary regulation of hedgehog pathway repression in tissue morphogenesis TIPE proteins

Many G-protein-coupled receptors (GPCRs) including EP4 are localized in cilia for modulating cAMP signaling

GPCRs in Neuroscience Heterotrimeric G proteins regulate planarian regeneration and behavior. The Illuminating the Understudied Druggable Proteome Conference. (Research Software Engineer) Senior Scientist – Native Mass Spectrometry Speculative Applications (Protein

yesterday for contributions to the field of mass spectrometry and establishing it as method to analyse proteins

September 2022 "G protein-coupled receptors (GPCRs) are signaling hubs in cell membranes that regulate

suppression of gut IEL effector functions linked to the dampening of proximal T cell receptor signaling in a protein-kinase-A-dependent

the gut-brain axis, have entered a strategic research collaboration to identify and validate novel G protein-coupled

October 2022 "Protease-activated receptor 2 (PAR2) is a G-protein-coupled receptor (GPCR) activated by