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452 items found for "Stefano Moro"
- Applications of Cryo-EM in small molecule and biologics drug design
biologics, such as vaccines, viral vectors, and gene therapy agents, has also become significantly more
- GRK2 in cardiovascular disease and its potential as a therapeutic target
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- Luciferase-based GloSensor™ cAMP assay: Temperature optimization and application to cell-based kinet
GloSensor™ cAMP assay can be applied to analyze signaling by a wide range of GPCRs for drug discovery" Read more
- Signaling pathways activated by sea bass gonadotropin-inhibitory hormone peptides in COS-7 cells...
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- Cell-Type-Specific Effects of the Ovarian Cancer G-Protein Coupled Receptor (OGR1) on Inflammation..
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- Exploiting Dependence of Castration-Resistant Prostate Cancer on the Arginine Vasopressin ...
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- Induced Human Regulatory T Cells Express the Glucagon-like Peptide-1 Receptor
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- Dynamic recognition of naloxone, morphine and endomorphin1 in the same pocket of µ-opioid receptors
Morphine, the most widely used analgesic, relieves severe pain by activating the μ-opioid receptor (MOR The mechanism by which the MOR distinguishes between the two is unclear. the pocket is critical for the agonistic effect of MOR. basis for the discovery of new ligands for MOR at the atomic level." Read more at the source #DrGPCR #GPCR #IndustryNews
- 📰 GPCR Weekly News, February 20 to 26, 2023
lipid polyunsaturation on dopamine D2 receptor ligand binding and signaling GPCR Binders, Drugs, and more Reviews, GPCRs, and more Cell-trafficking impairment in disease-associated LPA6 missense mutants and
- 📰 GPCR Weekly News, December 18 to 31, 2023
paramamosain Reshaping the yeast galactose regulon via GPCR signaling cascade GPCR Binders, Drugs, and more genetic landscape of GPCR signaling through phenotypic profiling in C. elegans Reviews, GPCRs, and more
- Chemokine receptor-targeted drug discovery: progress and challenges
overexpressed and promote cancer progression, and use promiscuous non-peptide antagonists able to target more substantiated the notion that redundancy is not a feature of the chemokine system (Nedjai et al. 2012), but more
- 📰 GPCR Weekly News, May 13 to 19, 2024
of the adhesion GPCR ADGRG6/GPR126 is a key regulator of receptor signaling GPCR Binders, Drugs, and more and treatment markers in hepatocellular carcinoma via GPCR-related genes analysis Reviews, GPCRs, and more
- Increased Anxiety-like Behaviors in Adgra1-/- Male But Not Female Mice are Attributable to...
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- PH-Binding Motif in PAR4 Oncogene: From Molecular Mechanism to Drug Design
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- Enhanced membrane binding of oncogenic G protein αqQ209L confers resistance to inhibitor YM-254890
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- Genome-scale CRISPR screening reveals that C3aR signaling is critical for rapid capture of fungi...
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- GPR15 expressed in T lymphocytes from RA patients is involved in leukocyte chemotaxis to the...
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- GPR3 expression in retinal ganglion cells contributes to neuron survival and accelerates axonal...
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- 📰 GPCR Weekly News, October 30 to November 4, 2023
the fat deposition in adipose tissues of finishing pigs via cAMP/PKA pathway GPCR Binders, Drugs, and more identifying physiologically relevant binding proteins of G-protein-coupled receptors Reviews, GPCRs, and more
- Regulator of G Protein Signaling 20 Correlates with Long Intergenic Non-Coding RNA (lincRNAs)...
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- Regulation of rod photoreceptor function by farnesylated G-protein γ-subunits
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- Fly casting with ligand sliding and orientational selection supporting complex formation of a GPCR..
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- High GPER expression in triple-negative breast cancer is linked to pro-metastatic pathways and...
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- Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify...
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- GASP1 enhances malignant phenotypes of breast cancer cells and decreases their response to...
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- Biased GPCR signaling by the native parathyroid hormone-related protein 1 to 141 relative to its...
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- Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells...
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- GPR125 (ADGRA3) is an autocleavable adhesion GPCR that traffics with Dlg1 to the basolateral...
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