Many G-protein-coupled receptors (GPCRs) including EP4 are localized in cilia for modulating cAMP signaling

yesterday for contributions to the field of mass spectrometry and establishing it as method to analyse proteins

acid derivatives as a new class of GPR34 antagonists Larixol is not an inhibitor of Gαi containing G proteins Immunology Context-dependent ciliary regulation of hedgehog pathway repression in tissue morphogenesis TIPE proteins Operational Highlights and Consolidated Results for the Third Quarter and First Nine Months of 2023 InterAx

the gut-brain axis, have entered a strategic research collaboration to identify and validate novel G protein-coupled

GPCRs in Neuroscience Heterotrimeric G proteins regulate planarian regeneration and behavior. The Illuminating the Understudied Druggable Proteome Conference. (Research Software Engineer) Senior Scientist – Native Mass Spectrometry Speculative Applications (Protein

September 2022 "G protein-coupled receptors (GPCRs) are signaling hubs in cell membranes that regulate

suppression of gut IEL effector functions linked to the dampening of proximal T cell receptor signaling in a protein-kinase-A-dependent

Axon regeneration in response to injury is determined by the interaction between the extracellular environment We demonstrate that the chemoreceptor genes, srg-36 and srg-37 , which encode G protein-coupled receptors

To target hard-to-drug targets like G protein-coupled receptors (GPCRs), more libraries, including better

October 2022 "Protease-activated receptor 2 (PAR2) is a G-protein-coupled receptor (GPCR) activated by

Here, 33 neuropeptide precursors and 48 putative neuropeptide G protein-coupled receptor (GPCR) genes

Dynamics of the Serotonin1A Receptor Utilizing Single Particle Tracking: Analysis of Diffusion Modes "G protein-coupled

Belgium – March 10, 2022 – Confo Therapeutics , a leader in the discovery of medicines targeting G-protein

partner GlaxoSmithKline PLC posted results Dec. 7 demonstrating activity against the omicron spike protein

Using purified Fzd proteins reconstituted in lipid nanodiscs, we investigated the factors that promote

We showed that the receptor is a member of the Octβ3 protein family, and an analysis using quantitative

inflammasome activation in macrophages "The putative medium-chain free fatty acid receptor GPR84 is a G protein-coupled

actin cytoskeleton in regulating the dynamics of the serotonin1A receptor, a crucial neurotransmitter G protein-coupled

silicon platform, announced a strategic collaboration to discover therapeutic antibodies against G protein-coupled

The cytoskeletal protein filamin A (FLNA) directly interacts with both somatostatin receptor type 2 (

Class B G protein-coupled receptors (GPCRs) are notoriously difficult to target by small molecules because

G protein-coupled receptors (GPCRs) are integral to cellular signaling, influencing a wide array of physiological

A conserved intracellular allosteric binding site (IABS) has recently been identified at several G protein-coupled

rodent model of 3-day recurrent hypoglycemia, we first checked expression of counterregulatory hormone G-protein

Identification of A2BAR as a potential target in colorectal cancer using novel fluorescent GPCR ligands "G-protein

G-protein coupled receptors (GPCRs) play a paramount role in diverse brain functions.

November 2022 "Recently determined structures of class C G protein-coupled receptors (GPCRs) revealed

Luciferase-based GloSensor™ cAMP assay: Temperature optimization and application to cell-based kinetic studies "G protein-coupled