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437 items found for "α(2A)-adrenergic receptor"
- PI(4,5)P 2-stimulated positive feedback drives the recruitment of Dishevelled to Frizzled in Wnt-β-c
September 2022 "In the Wnt-β-catenin pathway, Wnt binding to Frizzled (Fzd) and LRP5 or LRP6 (LRP5/6) co-receptors
- Neuropeptide S Encodes Stimulus Salience in the Paraventricular Thalamus
Taking advantage of a striking deficit of both NPS receptor (NPSR1) and NPS precursor knockout mice in
- Addex's strategic partner The Janssen Pharmaceutical Companies of Johnson & Johnson, Inc. has...
ADX71149 is a selective metabotropic glutamate type 2 (mGlu2) receptor positive allosteric modulator
- Effect Delta-9-tetrahydrocannabinol and cannabidiol on milk proteins and lipid levels in HC11 cells
In conclusion, 10μM THC and CBD altered the differentiation of HC11 cells, in part via the CB2 receptor
- Pharmacological targeting of cGAS/STING-YAP axis suppresses pathological angiogenesis and...
of cGAS/STING-YAP signaling by both a small-molecule STING agonist, SR-717, and a G protein-coupled receptor
- Biphasic activation of β-arrestin 1 upon interaction with a GPCR revealed by methyl-TROSY NMR
β-arrestins (βarrs) play multifaceted roles in the function of G protein-coupled receptors (GPCRs). βarrs
- Latrophilin-1 drives neuron morphogenesis and shapes chemo- and mechanosensation-dependent ...
specific LAT-1-positive neurons and first insights into the genetic network that is modulated by the receptor
- Applications of Cryo-EM in small molecule and biologics drug design
crystallography, by cryo-EM has enabled insights into important drug target families such as G protein-coupled receptors
- HDX-MS-optimized approach to characterize nanobodies as tools for biochemical and structural ...
in multiple immune signaling processes and is dependent on activation by Ras and G protein-coupled receptors
- Enhanced membrane binding of oncogenic G protein αqQ209L confers resistance to inhibitor YM-254890
October 2022 "Heterotrimeric G proteins couple activated G protein-coupled receptors (GPCR) to intracellular
- GPR3 expression in retinal ganglion cells contributes to neuron survival and accelerates axonal...
G protein-coupled receptor 3 (GPR3) belongs to the class A rhodopsin-type GPCR family and is highly expressed
- A Model for the Signal Initiation Complex Between Arrestin-3 and the Src Family Kinase Fgr
Arrestins regulate a wide range of signaling events, most notably when bound to active G protein-coupled receptors
- Structural dynamics of Smoothened (SMO) in ciliary membrane and its interaction with membrane lipids
September 2022 "The Smoothened receptor (SMO, a 7 pass transmembrane domain, Class F GPCR family protein
- Chemical signaling regulates axon regeneration via the GPCR-Gqα pathway in Caenorhabditis elegans
We demonstrate that the chemoreceptor genes, srg-36 and srg-37 , which encode G protein-coupled receptors
- Deficiency of β-arrestin2 alleviates apoptosis through GRP78-ATF6-CHOP signaling pathway in ...
β-arrestin2 is a key protein that mediates desensitization and internalization of G protein-coupled receptors
- Neuronal Gα subunits required for the control of response to polystyrene nanoparticles in the ...
The aim of this study was to identify Gα proteins mediating function of neuronal G protein-coupled receptors
- Adhesion GPCR Consortium Newsletter - May 2024
BAI1 is expressed in the afferent spiral ganglion neurons in the mouse cochlea where it localizes AMPA receptors