ADX71149 is a selective metabotropic glutamate type 2 (mGlu2) receptor positive allosteric modulator

recurrent hypoglycemia, we first checked expression of counterregulatory hormone G-protein coupled receptors

β-arrestins (βarrs) play multifaceted roles in the function of G protein-coupled receptors (GPCRs). βarrs

In conclusion, 10μM THC and CBD altered the differentiation of HC11 cells, in part via the CB2 receptor

of cGAS/STING-YAP signaling by both a small-molecule STING agonist, SR-717, and a G protein-coupled receptor

crystallography, by cryo-EM has enabled insights into important drug target families such as G protein-coupled receptors

in multiple immune signaling processes and is dependent on activation by Ras and G protein-coupled receptors

October 2022 "Heterotrimeric G proteins couple activated G protein-coupled receptors (GPCR) to intracellular

G protein-coupled receptor 3 (GPR3) belongs to the class A rhodopsin-type GPCR family and is highly expressed

The surface expression of pattern recognition receptors, such as TLR2 and TLR4, provides platelets with

We demonstrate that the chemoreceptor genes, srg-36 and srg-37 , which encode G protein-coupled receptors

β-arrestin2 is a key protein that mediates desensitization and internalization of G protein-coupled receptors

The aim of this study was to identify Gα proteins mediating function of neuronal G protein-coupled receptors

Exendin-4, and possibly through G protein-coupled receptors (GPCRs), increases levels of cAMP and upregulates

BAI1 is expressed in the afferent spiral ganglion neurons in the mouse cochlea where it localizes AMPA receptors

The TM helices 1–5 form a structurally conserved domain that facilitates the assembly of the helical and catalytic domains. Neutralization of the negatively charged extracellular pocket Ex1 destabilizes the cytosolic helical domain The TM domain acts as a functional component of Cya, guiding the assembly of the catalytic domain and