Search Results
439 items found for "Dr. Albert Kooistra"
- Interplay between G protein-coupled receptors and nanotechnology
Immunology Structural and molecular insights into GPCR function GPCR Activation and Signaling More from Dr GPCR Create an account and get our contributors articles in your inbox Subscribe to the Dr. Follow the Dr. GPCR News and get weekly notifications about the GPCR field Share < Previous Next >
- Investigating isoform switching in RHBDF2 and its role in neoplastic growth in breast cancer
Immunology Structural and molecular insights into GPCR function GPCR Activation and Signaling More from Dr GPCR Create an account and get our contributors articles in your inbox Subscribe to the Dr. Follow the Dr. GPCR News and get weekly notifications about the GPCR field Share < Previous Next >
- Functional Assessment of Cancer-Linked Mutations in Sensitive Regions of Regulators of G Protein Signaling Predicted by Three-Dimensional Missense Tolerance Ratio Analysis
Immunology Structural and molecular insights into GPCR function GPCR Activation and Signaling More from Dr GPCR Create an account and get our contributors articles in your inbox Subscribe to the Dr. Follow the Dr. GPCR News and get weekly notifications about the GPCR field Share < Previous Next >
- Regulator of G protein signaling protein 6 alleviates acute lung injury by inhibiting inflammation and promoting cell self-renewal in mice
Immunology Structural and molecular insights into GPCR function GPCR Activation and Signaling More from Dr GPCR Create an account and get our contributors articles in your inbox Subscribe to the Dr. Follow the Dr. GPCR News and get weekly notifications about the GPCR field Share < Previous Next >
- LPA1-mediated inhibition of CXCR4 attenuates CXCL12-induced signaling and cell migration
Immunology Structural and molecular insights into GPCR function GPCR Activation and Signaling More from Dr GPCR Create an account and get our contributors articles in your inbox Subscribe to the Dr. Follow the Dr. GPCR News and get weekly notifications about the GPCR field Share < Previous Next >
- Ep 95 with Chris Langmead
Dr. Langmead on the web Monash University T witter Google Scholar Linkedin PubMed Monash Neuromedicines Dr
- Leaving for City Center | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Leaving for City Center Coming Soon < Previous Session Next Session >
- Distinct sub-cellular signal propagation as a component of functional selectivity
Dr. ResearchGate Twitter LinkedIn Universite de Montreal- Department of Biochemistry and Molecular Medicine Dr
- Genetic Deletion of Atypical VGLUT3 Rescues Huntington’s Disease Phenotype and Neurodegeneration in zQ175 Mice
Karim Ibrahim on the web X (Twitter) Google Scholar Dr.
- GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment
Immunology Structural and molecular insights into GPCR function GPCR Activation and Signaling More from Dr GPCR Create an account and get our contributors articles in your inbox Subscribe to the Dr. Follow the Dr. GPCR News and get weekly notifications about the GPCR field Share < Previous Next >
- Coffee Break with lights snacks | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Coffee Break with lights snacks Complimentary < Previous Session Next Session >
- Unbiased multitissue transcriptomic analysis reveals complex neuroendocrine regulatory networks mediated by spinal cord injury-induced immunodeficiency
Immunology Structural and molecular insights into GPCR function GPCR Activation and Signaling More from Dr GPCR Create an account and get our contributors articles in your inbox Subscribe to the Dr. Follow the Dr. GPCR News and get weekly notifications about the GPCR field Share < Previous Next >
- Removing the GPCR-mediated brake on exocytosis enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity
Dr. Heidi Hamm on the web The Hamm Lab Vanderbilt School of Medicine Pubmed Google Scholar LinkedIn Twitter Dr
- Mexico City Nocturnal Tour, Food and drinks | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Mexico City Nocturnal Tour, Food and drinks Coming Soon < Previous Session Next Session >
- Biased agonism at the GLP-1 receptor: from structure to animal models of disease
Sexton is also a co-founder of Septerna Inc. " Patrick Sexton on the web CCeMMP Monash University Dr.
- Session IX / Technology capsule: Light on aGPCR signaling and function | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Session IX / Technology capsule: Light on aGPCR signaling and function NovoiSMART - A new platform for GPCR antibody drug discovery Abstract Developing monoclonal antibody drugs against GPCRs and other multi-pass transmembrane targets, such as ion channels, remains a significant challenge. Novoprotein developed a NovoiSMART technology, utilizing mRNA-based immunization, which can overcome these obstacles by producing high-quality antibodies that more accurately mimic natural protein structures. This approach contrasts with other antigen forms like peptides or DNA, which face limitations in structural integrity and immunogenicity. mRNA technology, demonstrated in the success of COVID-19 vaccines, is emerging as a promising method for antibody discovery. Several case studies of GPCR and other multi-pass transmembrane targets are presented, including GPRC5D, Claudin 6 and Napi2b. These studies show that mRNA immunization yields higher antibody titers and greater epitope diversity compared to other methods. These examples underscore the potential of NovoiSMART technology in developing highly specific antibodies for complex targets, with implications for overcoming challenges like drug resistance and tumor escape. About Gavin Zhang Gavin is a currently a director of business and operations at Novoprotein Scientific. His research experience includes phylogenetics and cancer epigenetics. Gavin Zhang on the web LinkedIn < Previous Session Next Session >
- Atypical Structure and Function of Typical Chemokine Receptors
The Ramsey Lab Amy Ramsey on the web University of Toronto Pubmed Google Scholar LinkedIn Twitter Dr.
- Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions
Source Classified GPCR News More from Dr. GPCR Share < Previous Next >
- Neuroimmune interplay during type 2 inflammation: symptoms, mechanisms and therapeutic targets in atopic diseases
Source Classified GPCR News More from Dr. GPCR Share < Previous Next >