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584 items found for "GPCR therapeutics"
- ShouTi Introduces Basecamp Bio as a Wholly Owned Subsidiary to Expand Pipeline and Partnerships
., a clinical-stage global biopharmaceutical company developing novel oral therapeutics to treat a wide Read more at the source #DrGPCR #GPCR #IndustryNews
- RGS7-ATF3-Tip60 Complex Promotes Hepatic Steatosis and Fibrosis by Directly Inducing TNFα
Signaling 7 (RGS7) in hyperlipidemia-dependent hepatic dysfunction. " Read more at the source #DrGPCR #GPCR
- Identification and functional characterization of the sulfakinin and sulfakinin receptor in the...
physiological functions in invertebrates through the interaction with G-protein-coupled receptors (GPCRs Read more at the source #DrGPCR #GPCR #IndustryNews
- Addex Expands Pipeline With Selective M4 Positive Allosteric Modulator Program For The Treatment ...
Screening Platform Ad Hoc Announcement Pursuant to Art. 53 LR Geneva, Switzerland, April 6, 2022 - Addex Therapeutics Read more at the source #DrGPCR #GPCR #IndustryNews
- Novo Nordisk moves to strengthen obesity efforts
Novo Nordisk is strengthening its position in the obesity space through a collaboration with EraCal Therapeutics Read more at the source #DrGPCR #GPCR #IndustryNews
- Protein Uncoupling as an Innovative Practice in Diabetes Mellitus Treatment: A Metabolic Disorder
Read more at the source #DrGPCR #GPCR #IndustryNews
- Discovery On Target, October 17-20, 2022, Boston, USA
and technologies, as well as target validation strategies for the discovery and development of novel therapeutic Read more at the source #DrGPCR #GPCR #IndustryNews
- Exploring pharmacological inhibition of G q/11 as an analgesic strategy
These can be used either as stand-alone therapeutics or to improve the safety profile of opioid drugs Read more at the source #DrGPCR #GPCR #IndustryNews
- Delineation of GPR15 receptor-mediated Gα protein signaling profile in recombinant mammalian cell
September 2022 "The GPR15 receptor is a G protein-coupled receptor (GPCR), which is activated by an endogenous Read more at the source #DrGPCR #GPCR #IndustryNews
- FSH and bone: Comparison between males with central versus primary hypogonadism
Read more at the source #DrGPCR #GPCR #IndustryNews
- Drug Discovery Picks Up the Pace, Stays on Target
drug efficacy analyses, and toxicity studies; technologies that stabilize G protein–coupled receptors (GPCRs Read more at the source #DrGPCR #GPCR #IndustryNews
- Amgen to Acquire Chemocentryx for $4 Billion in Cash
., (NASDAQ: CCXI), a biopharmaceutical company focused on orally administered therapeutics to treat autoimmune Read more at the source #DrGPCR #GPCR #IndustryNews
- Learn more about Neurocrine Biosciences with their new video
Read more at the source #DrGPCR #GPCR #IndustryNews
- Molecular basis for variations in the sensitivity of pathogenic rhodopsin variants to 9-cis-retinal
Read more at the source #DrGPCR #GPCR #IndustryNews Subscribe to the Newsletter HERE
- Ginsenoside Rg5 allosterically interacts with P2RY12 and ameliorates deep venous thrombosis by...
Read more at the source #DrGPCR #GPCR #IndustryNews
- Discovery of 3(2-aminoethyl)-thiazolidine-2,4-diones as a novel chemotype of sigma-1 receptor ligand
August 2022 "Abstract Sigma receptor is a transmembrane non-GPCR protein expressed mainly in the endoplasmic Read more at the source #DrGPCR #GPCR #IndustryNews
- 2nd IRN i-GPCRnet, September 30 to October 1st, 2022. University of Wurzburg, Germany
Read more at the source #DrGPCR #GPCR #IndustryNews
- A central alarm system that gates multi-sensory innate threat cues to the amygdala
The identification of unified innate threat pathways may provide insights into developing therapeutic Read more at the source #DrGPCR #GPCR #IndustryNews
- Carola Weiss joins InterAx Biotech AG as VP Business Development
Read more at the source #DrGPCR #GPCR #IndustryNews
- Sweet taste receptor agonists attenuate macrophage IL‐1β expression and eosinophilic inflammation...
Eosinophilic inflammation is a hallmark of refractory chronic rhinosinusitis (CRS) and considered a major therapeutic (ECRS) via macrophage IL‐1β overproduction, thereby suggesting autophagy regulation as a potential therapeutic We sought to investigate the therapeutic potential of autophagy‐enhancing agent, trehalose, or related Methods We investigated the therapeutic effects of trehalose and saccharin on macrophage IL‐1β production Read more at the source #DrGPCR #GPCR #IndustryNews
- Immunomodulatory Role of Neuropeptides in the Cornea
maintaining the homeostasis of the ocular surface, alterations in disease settings, and the possible therapeutic Read more at the source #DrGPCR #GPCR #IndustryNews
- TAS2R supports odontoblastic differentiation of human dental pulp stem cells in the inflammatory...
The expression markers related to odontoblastic differentiation of hDPSCs were observed by qPCR and chemical The G protein and intracellular Ca2+ were detected, respectively, by qPCR and Fluo-4AM Ca2+ fluorescent Read more at the source #DrGPCR #GPCR #IndustryNews
- Fentanyl activates ovarian cancer and alleviates chemotherapy-induced toxicity via opioid...
Read more at the source #DrGPCR #GPCR #IndustryNews
- Neurotransmitters: Potential Targets in Glioblastoma
Read more at the source #DrGPCR #GPCR #IndustryNews
- Jan Steyaert Named 2022 Jacob and Louise Gabbay Award Winner
combination of Steyaert’s fundamental research and his ability to apply the research to the development of therapeutic Read more at the source #DrGPCR #GPCR #IndustryNews
- Targeting the M1 muscarinic receptor in neurodegenerative disease
Translational Sciences Associate Director at Sosei Heptares, recently presented at the Keystone Symposia GPCR the role of the muscarinic M1 receptor in cognitive and neurodegenerative disorders and the potential therapeutic Read more at the source #DrGPCR #GPCR #IndustryNews
- Naggie and Rajagopal Elected Members of American Society for Clinical Investigation
" Read more at the source #DrGPCR #GPCR #IndustryNews
- C1-inhibitor influence on platelet activation by thrombin receptors agonists
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