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468 items found for "G-protein coupled receptor signaling"
- Search for safer pain relief advances with new engineered compounds
pain-relieving compounds that, like morphine and other drugs, provide relief via activation of opioid receptors
- Addex Therapeutics Completes Patient Enrollment For Dipraglurant Blepharospasm Phase 2 Clinical ...
Dipraglurant selectively targets the metabotropic glutamate receptor subtype 5 (mGlu5) through allosteric
- California gold rush for Sosei Heptares
The vision is to develop novel muscarinic receptor agonists for schizophrenia and other neuropsychiatric
- Addex Expands Pipeline With Selective M4 Positive Allosteric Modulator Program For The Treatment ...
drug discovery and development, announced today that it has moved a selective and potent M4 muscarinic receptor
- C3aR plays both sides in regulating resistance to bacterial infections
results in the production of bioactive C3a, a product of C3 cleavage, which interacts with membrane-bound receptor
- Identification of hub genes in the subacute spinal cord injury in rats
correlation network analysis (WGCNA) were performed using R software, and functional enrichment analysis and protein–protein
- Positive Recommendation for Use of TAVNEOS™ (avacopan) in ANCA Vasculitis Adopted by European ...
authorization for the Company’s TAVNEOS (avacopan), an orally administered selective complement 5a receptor
- Professor Charlotte Deane Joins Exscientia as Chief Scientist of Biologics AI
will focus on the application of artificial intelligence (AI), machine learning, and the design of protein of Oxford, where she is currently Professor of Structural Bioinformatics and leads the University’s Protein
- Addex's strategic partner The Janssen Pharmaceutical Companies of Johnson & Johnson, Inc. has...
ADX71149 is a selective metabotropic glutamate type 2 (mGlu2) receptor positive allosteric modulator
- OMass Therapeutics's founder, Carol Robinson, has been awarded the prestigious Louis-Jeantet ...
yesterday for contributions to the field of mass spectrometry and establishing it as method to analyse proteins
- First in Human: Early-stage COVID therapies hold promise against omicron variant
partner GlaxoSmithKline PLC posted results Dec. 7 demonstrating activity against the omicron spike protein
- Dynamics of tumor-associated macrophages in a quantitative systems pharmacology model of...
Quantitative systems pharmacology (QSP) modeling is an emerging mechanistic computational approach that couples
- Molecular basis for variations in the sensitivity of pathogenic rhodopsin variants to 9-cis-retinal
Evaluation of the observed shifts relative to thermodynamic estimates for the coupling between binding
- Orion and Peptilogics are pursuing AI-driven drug discovery to explore new functional chemical ...
new functional chemical space and precision-engineer therapeutics with enhanced potency and tailored signaling
- Unconventional GPCR-PKA Communication in the Hedgehog Pathway
Learn about communication between GPCRs and PKA, Class F GPCR Smoothened & the Hedgehog signaling pathway
- Dr. Adriano Marchese - Dr. GPCR Podcast
Learn about his remarkable career and research in #GPCR signaling and trafficking.
- Time is your enemy, GPCRs are your friend
Stuart Maudsley on how an aging physiological context affects #GPCR signaling #drgpcr.
- Structure of Mycobacterium tuberculosis Cya, an evolutionary ancestor of the mammalian membrane...
Although the vital role of ACs in cellular signalling is well established, the function of their transmembrane
- A central alarm system that gates multi-sensory innate threat cues to the amygdala
Previous findings suggest that parallel pathways independently relay innate threat signals from different
- Targeted Therapies to Reduce Side Effects in Modern Drug Development
development approaches include a range of techniques leveraging structural biology, immunology, cell signaling
