Search Results
464 items found for "protease-activated receptors (PARs)"
- Structure of Mycobacterium tuberculosis Cya, an evolutionary ancestor of the mammalian membrane...
charged extracellular pocket Ex1 destabilizes the cytosolic helical domain and reduces the catalytic activity guiding the assembly of the catalytic domain and providing the means for direct regulation of catalytic activity
- Engineered synaptic tools reveal localized cAMP signaling in synapse assembly
We show that locally restricted suppression of postsynaptic cAMP levels or of cAMP-dependent protein-kinase activity severely impairs excitatory synapse formation without affecting neuronal maturation, dendritic
- ChemoCentryx Announces EU Approval of TAVNEOS® (avacopan) for the Treatment of ANCA-Associated ...
combination with a rituximab or cyclophosphamide regimen for the treatment of adult patients with severe, active
- Michel Bouvier appointed Knight of the Ordre national du Québec
The rank of Knight specifically rewards the implementation of an exemplary activity in a particular field
- Inversago Pharma Completes Phase 1 Clinical Trial on First-in-Class, Peripheral CB1 Blocker and...
tolerability and pharmacokinetic results from the trial warrant further investigation, and the Company will actively
- Primary cilia and SHH signaling impairments in human and mouse models of Parkinson’s disease
Thus, increased SHH activity due to ciliary dysfunction may be required for the development of pathoetiological
- Dynamics of tumor-associated macrophages in a quantitative systems pharmacology model of...
The combination of the anti-PD-L1 antibody atezolizumab and nab-paclitaxel has shown clinical activity
- Identification of hub genes in the subacute spinal cord injury in rats
correlation network analysis (WGCNA) were performed using R software, and functional enrichment analysis and protein–protein
- 📰 GPCR Weekly News, April 29 to May 5, 2024
The story behind how Dr.GPCR came to be, the people behind the process, the great anecdotes, and what
- Reflections on My PhD Journey: Lessons Learned
approach not only ensures that you remain on top of your findings but also makes the thesis-writing process Trust the process, lean on your support system, and remember: the journey itself is as transformative
- Ginsenoside Rg5 allosterically interacts with P2RY12 and ameliorates deep venous thrombosis by...
DVT formation is a time-dependent inflammatory process in which NETosis plays an important role.
- Endocannabinoid System in the Neuroendocrine Response to Lipopolysaccharide-induced Immune Challenge
Here we explore which actors and molecular mechanisms are involved in these processes."
- TAS2R supports odontoblastic differentiation of human dental pulp stem cells in the inflammatory...
The G protein and intracellular Ca2+ were detected, respectively, by qPCR and Fluo-4AM Ca2+ fluorescent
- New Resources in GPCRdb
Gáspár Pándy-Szekeres ) will present and demonstrate the newest resources of the GPCRdb: 1) the new G protein
- OMass Therapeutics's founder, Carol Robinson, has been awarded the prestigious Louis-Jeantet ...
yesterday for contributions to the field of mass spectrometry and establishing it as method to analyse proteins
- Targeted Therapies to Reduce Side Effects in Modern Drug Development
approach to kill fast-growing cancer cells, has the drawback of causing damage to healthy cells in the process