Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Coffee Break 5 Date & Time Saturday, November 4th / 9:55 AM Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

! Widget Didn’t Load Check your internet and refresh this page. If that doesn’t work, contact us. GPCR Retreat Program < Back to schedule Cannabinoid compounds to augment L-DOPA treatment in Parkinson's Disease Date & Time Friday, November 3rd / 9:20 AM Abstract Coming Soon About Ali Salahpour "Dr. Salahpour did his undergrad (1993-1996) and PhD (1996-2002) at University of Montreal in the Department of Biochemistry. His PhD work was under the supervision of Dr. Michel Bouvier working on the topic of GPCR dimerization/oligomerization. In November of 2002, he joined the lab of Dr. Marc Caron at Duke University for his post-doctoral training. In the Caron lab, Dr. Salahpour worked on Dopamine Transporter and its role on regulating dopamine transmission and homeostasis. In April 2009, he joined the Department of Pharmacology and Toxicology at University of Toronto and has continued working on dopamine transmission and homeostasis and the role of several of key modulators of the dopamine system, including the dopamine transporter (DAT), the Vesicular Monoamine Transporter 2 (VMAT2), Tyrosine Hydroxylase (TH) and Trace Amine Associate Receptor 1 (TAAR1)." Ali Salahpour on the web University of Toronto Pubmed Google Scholar Twitter Dr. GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Welcome Remarks Date & Time Thursday, November 2nd / 1:30 PM Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Coffee Break 3 Date & Time Friday, November 3rd / 10:25 AM Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule A journey from Duke to McGill along the dopamine circuit Date & Time Friday, November 3rd / 8:55 AM Abstract Coming Soon About Bruno Giros "Bruno Giros' lab is dedicated to investigating how molecular changes at the nerve synapse might impact integrated behavior and what we might learn from these mechanisms to cure mental illness. After a doctoral training at the Pierre and Marie Curie University in Paris and a short internship at Genentech Inc. in South San Francisco, he joined the CNRS as a Research Fellow in 1987 in the INSERM Laboratory directed by Jean-Charles Schwartz in Paris, where he cloned and characterized dopamine D2 and D3 receptor subtypes. From 91 to 94, he was an assistant professor at Duke University in North Carolina, working with Marc Caron on the characterization of several neurotransmitter transporters and kinases and establishing the first knock- out for these genes. In 1999, back in France, Dr. Giros created the INSERM/CNRS laboratory on the "Neurobiology of Psychiatric Disorders", at the University of Paris-Sorbonne. Since 2008, he arrived at McGill University with a Canada Research Chair. At McGill, his laboratory has two main axes of research: 1) Studying interindividual vulnerability to chronic stress and depression and; 2) Understand the role of phenotypically defined subpopulations of striatal neurons in motor and cognitive functions." Brunos Giros on the web The Douglas Research Centre McGill University Pubmed Google Scholar LinkedIn Dr. GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Genetic Deletion of Atypical VGLUT3 Rescues Huntington’s Disease Phenotype and Neurodegeneration in zQ175 Mice Date & Time Friday, November 3rd / 2:10 PM About Karim Ibrahim "A postdoctoral researcher, interested in studying G-protein coupled receptors and their role in neurodegenerative disorders, including Alzheimer's and Huntington's diseases." Karim Ibrahim on the web X (Twitter) Google Scholar Dr. GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

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Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program Download PDF Program Thursday, November 2nd / 11:00 AM - 1:30 PM Registration Read More Thursday, November 2nd / 1:30 PM Welcome Remarks Read More Thursday, November 2nd / 1:45 PM - 2:45 PM Trainee Symposium I Eric Johansen , Johns Hopkins University Grace Mazarura , McGill University Émile Breault, Université de Sherbrooke Bassam Albraidy , Ottawa Hospital Research Institute Read More Thursday, November 2nd / 2:45 PM Coffee Break 1 Read More Thursday, November 2nd / 3:00 PM - 4:00 PM Trainee Symposium II Amr Mousa , University of Western Ontario Louis-Philippe Picard , University of Toronto Remi Janicot , Boston University Meredith Skiba , Harvard University Read More Thursday, November 2nd / 4:00 PM Check In Read More Thursday, November 2nd / 4:30 PM "Have a nice weekend, and I'll see you tomorrow!": RAMP-interacting GPCR Pathways Inaugural Marc G. Caron Keynote Lecture Kathleen M. Caron University of North Carolina at Chapel Hill Read More Thursday, November 2nd / 5:30 PM Welcome Reception and Poster Session 1 Read More Thursday, November 2nd / 8:00 PM Dinner 1 Read More Friday, November 3rd / 7:30 AM Breakfast 1 Read More Friday, November 3rd / 8:30 AM Dopamine-Mediated Motor Recovery after Ischemic Stroke Mario Tiberi Ottawa Hospital Research Institute Read More Friday, November 3rd / 8:55 AM A journey from Duke to McGill along the dopamine circuit Bruno Giros McGill University Read More Friday, November 3rd / 9:20 AM Cannabinoid compounds to augment L-DOPA treatment in Parkinson's Disease Ali Salahpour University of Toronto Read More Friday, November 3rd / 9:45 AM Pharmacological and Genetic Preclinical Models of Ghrelin Receptor Functional Selectivity to Investigate Metabolic Disease Pathophysiology Joshua Gross Duke University Medical Center Read More Friday, November 3rd / 10:25 AM Coffee Break 3 Read More Friday, November 3rd / 10:40 AM Regulation and role of mitochondria delta opioid receptors Louis Gendron Université de Sherbrooke Read More Friday, November 3rd / 11:05 AM Biased agonism at the GLP-1 receptor: from structure to animal models of disease Patrick Sexton Monash University Read More Friday, November 3rd / 11:30 AM Complex Allosteric Cannabinoid Receptor Pharmacology Robert Laprairie University of Saskatchewan Read More Friday, November 3rd / 11:55 AM Unveiling Non-Canonical Functions for Gαq Signaling Pathways Poster Talk Catalina Ribas University Autonoma of Madrid Read More Friday, November 3rd / 12:10 PM Lunch 1 Read More Friday, November 3rd / 1:30 PM Interaction with the cell adhesion molecule NEGR1 affects mGluR5 cell signalling Fabiola Ribeiro Federal University of Minas Gerais, Brazil Read More Friday, November 3rd / 1:55 PM A positive Allosteric Modulator of M1 Acetylcholine Receptors Improves Cognitive Deficits in Male and Female Alzheimer’s Mice Khaled Abdelrahman The University of British Columbia Read More Friday, November 3rd / 2:10 PM Genetic Deletion of Atypical VGLUT3 Rescues Huntington’s Disease Phenotype and Neurodegeneration in zQ175 Mice Poster Talk Karim Ibrahim University of Ottawa Read More Friday, November 3rd / 2:45 PM Removing the GPCR-mediated brake on exocytosis enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity Heidi Hamm Vanderbilt University Read More Friday, November 3rd / 3:00 PM Coffee Break 4 Read More Friday, November 3rd / 3:30 PM G Proteins and GPCRs in Cancer: Novel Precision Targeted and Immunotherapies J. Silvio Gutkind UC San Diego Read More Friday, November 3rd / 3:55 PM Inhibition of Relaxin Autocrine Signaling Confers Therapeutic Vulnerability in Ovarian Cancer Robert Rottapel University of Toronto Read More Friday, November 3rd / 4:20 PM Developing a PROTAC to Degrade the Constitutively Active Onco-GPCR in Uveal Melanoma Poster Talk Victoria Rasmussen Rockefeller University Read More Friday, November 3rd / 4:35 PM Targeting adenosine signaling for immuno-oncology John Stagg CHUM, Université de Montréal Read More Friday, November 3rd / 5:00 PM Poster Session #2 Read More Friday, November 3rd / 7:00 PM Dinner 2 Read More Friday, November 3rd / 9:30 PM Board Meeting To discuss the next GPCR Retreat All PIs welcome Read More Saturday, November 4th / 7:30 AM Breakfast 2 Read More Saturday, November 4th / 8:15 AM Distinct sub-cellular signal propagation as a component of functional selectivity Michel Bouvier Université de Montréal Read More Saturday, November 4th / 8:40 AM Biochemical Mechanisms Underlying Location Bias in GPCR Signaling Sudarshan Rajagopal Duke University Medical Center Read More Saturday, November 4th / 9:05 AM Structure-based discovery of functionally selective 5-HT1A receptor agonists Peter Gmeiner Friedrich-Alexander University of Erlangen-Nürnberg Read More Saturday, November 4th / 9:30 AM Atypical Structure and Function of Typical Chemokine Receptors Tracy Handel UC San Diego Read More Saturday, November 4th / 9:55 AM Coffee Break 5 Read More Saturday, November 4th / 10:10 AM Using food perception and bioamine signaling networks to slow aging Scott Leiser University of Michigan Read More Saturday, November 4th / 10:35 AM Interrogating Multiscale Receptors Functions in Space Martin Beaulieu University of Toronto Read More Saturday, November 4th / 11:00 AM Atypical Structure and Function of Typical Chemokine Receptors Amy Ramsey University of Toronto Read More Saturday, November 4th / 11:30 AM Illuminating Functional Selectivity and Allosterism at GPCRs. Hyman B. Niznik Keynote Lecture Stephane Laporte McGill University Read More Saturday, November 4th / 12:30 PM Closing Remarks. Lunch and farewell Read More Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

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Meet Dr. GPCR Summit Partners - Click to Explore - Summit 2021 Full Schedule & Details Dr. GPCR Summit 2021 Live Talk Schedule GPCRdb Resources Dr. David Gloriam, Dr. Albert Kooistra, Gaspar Pandy-Szekeres September 13, 2021 at 2:00:00 PM Learn More >> CXCR4 heteromers as novel cancer targets Juan José Fung, Ph.D., Pina Cardarelli, Ph.D., September 13, 2021 at 5:00:00 PM Learn More >> Unconventional GPCR Signaling in the Hedgehog Pathway Dr. Ben Myers September 13, 2021 at 6:00:00 PM Learn More >> The Phosphorylation Barcode as a Mechanism of Biased β-arrestin 2 Recruitment and Conformation at CXCR3 Dylan S. Eiger September 13, 2021 at 7:00:00 PM Learn More >> A distinct activation mechanism in GPCR dimers: Insights from cryo-EM snapshots of the entire Class D1 GPCR activation pathway Vaithish Velazhahan September 13, 2021 at 8:00:00 PM Learn More >> Heat Shock Protein 90 is a Novel Opioid Receptor Signaling Regulator that can be Targeted to Improve Opioid Therapy Dr. John Streicher September 13, 2021 at 9:00:00 PM Learn More >> Through the Looking-Glass: Structure-Based Drug Discovery across the GPCRome Dr. Chris de Graaf September 14, 2021 at 12:00:00 PM Learn More >> Designer G protein-coupled receptors as tools to identify novel targets for antidiabetic and anti-obesity drugs Jürgen Wess September 14, 2021 at 1:00:00 PM Learn More >> "Toolboxing" solid-state NMR spectroscopy for GPCR studies Dr. Jiafei Mao September 14, 2021 at 2:00:00 PM Learn More >> GPCRomics: Identifying novel GPCR targets in health and disease Paul A. Insel September 14, 2021 at 3:00:00 PM Learn More >> A Funny Thing Happened at the Dr. GPCR Summit Dr. Robert Lefkowitz, Dr. Randy Hall September 14, 2021 at 5:00:00 PM Learn More >> Twist Biopharma: Synthetic DNA Technologies Enable Fast and Responsive anti-GPCR Antibody Discovery and Optimization Dr. Aaron K. Sato September 14, 2021 at 7:00:00 PM Learn More >> Advancing GPCR drug discovery with bioSensAll® platform technology Dr. Meriem Semache September 15, 2021 at 2:00:00 PM Learn More >> GPCR activation mechanisms across classes and macro/micro scales Dr. David Gloriam September 15, 2021 at 6:00:00 PM Learn More >> Hydroxycarboxylic acid receptor 3 and GPR84 signaling with potential implications for immune cell function Claudia Stäubert September 15, 2021 at 7:00:00 PM Learn More >> Engineering a human GPCR to create self-tunable engineered yeast probiotics for the treatment of inflammatory bowel disease Benjamin M. Scott September 15, 2021 at 8:00:00 PM Learn More >> The challenges of targeting RXFP1, the receptor for the heart failure drug candidate relaxin, with peptide mimetics and small molecules Ross AD Bathgate September 15, 2021 at 9:00:00 PM Learn More >> Profiling of GPCR complexes Kevin Pfleger September 16, 2021 at 12:00:00 PM Learn More >> Phosphorylation of the M1 muscarinic acetylcholine receptor protects from neurodegenerative disease Miriam Scarpa September 16, 2021 at 1:00:00 PM Learn More >> Innate Proximity: Utilizing the Inherent Physicality of Receptor Interactions for Drug Development Dr. Ajay Yekkirala September 16, 2021 at 2:00:00 PM Learn More >> Chaperoning G protein-coupled receptors Ya-Xiong Tao September 16, 2021 at 3:00:00 PM Learn More >> Where a Ph.D. Can Lead Dr. Brian Arey, Dr. Samuel Hoare, Dr. Ajay Yekkirala, Dr. Stephanie Val September 16, 2021 at 5:00:00 PM Learn More >> FR900359: nature’s weapon and treasure trove for basic and translational research Evi Kostenis September 17, 2021 at 5:00:00 PM Learn More >> Molecular basis of adhesion GPCR activation Dr. Demet Araç September 17, 2021 at 6:00:00 PM Learn More >> Structure-guided drug discovery Dr. Bryan Roth September 17, 2021 at 7:00:00 PM Learn More >> Nanobody tethering to dissect GPCR pharmacology Dr. Ross Cheloha September 17, 2021 at 8:00:00 PM Learn More >> Structure and dynamics of GPCRs: lessons from cryo-EM Dr. Patrick M. Sexton September 17, 2021 at 9:00:00 PM Learn More >> Meet Dr. GPCR Summit Partners - Click to Explore - Tags Dr. GPCR Summit Dr. GPCR Summit 2021 Dr. GPCR Summit 2021 Pre-Recorded Talks Dr. GPCR Summit 2021Live Talks

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