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565 items found for "class C GPCR"
- Addex Expands Pipeline With Selective M4 Positive Allosteric Modulator Program For The Treatment ...
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- Addex Therapeutics Completes Patient Enrollment For Dipraglurant Blepharospasm Phase 2 Clinical ...
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- Crinetics Pharmaceuticals Announces Pricing Of Underwritten Common Stock Offering
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- Inversago Pharma Announces Dosing of First Participant with Metabolic Syndrome in Phase 1B ...
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- Confo Therapeutics Doses First Subjects In Phase 1 Clinical Trial Of CFTX-1554 For The Treatment ...
Confo Therapeutics , a leader in the discovery of medicines targeting G-protein coupled receptors (GPCRs pharmacokinetics of CFTX-1554 in healthy subjects (NCT05260658). " Read more at the source #DrGPCR #GPCR
- Crinetics Pharmaceuticals Expands Executive Team With Appointment Of James Hassard As Chief ...
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- Sosei Heptares reported its FY2021 financial result and provided an update on operational activities
February 2022 Read more at the source #DrGPCR #GPCR #IndustryNews
- Trevena Announce Submission of New Drug Application in China for OLINVYK® by its Partner Jiangsu ...
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- InterAx Biotech AG and Boehringer Ingelheim take collaborate to unlock orphan targets leveraging ...
Collaborative efforts aim to accelerate and improve the prediction of first-in-class small molecule agonists for a challenging orphan GPCR for a highly relevant therapeutic need. 💊 InterAx Biotech AG discovery successfully applied in projects with biopharmaceutical companies and also used in-house to discover first-in-class #ai #biotech #systemsbiology #drugdiscovery #gpcr #deeptech #orphandrugs #pharma #partnerships #AI4drugdiscovery " Read more at the source #DrGPCR #GPCR #IndustryNews
- ShouTi Pharma has a brand new website
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- Learn more about Neurocrine Biosciences with their new video
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- Perkins’ Head of Molecular Endocrinology and Pharmacology, Professor Kevin Pfleger, was appointed...
the Australasian Pharmaceutical Science Association ( APSA ).” " Read more at the source #DrGPCR #GPCR
- First in Human: Early-stage COVID therapies hold promise against omicron variant
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- VIB spin-off Confo Therapeutics Enters Collaborative Agreement with Regeneron
December 2021 "30/11/2021 Confo will work together with Regeneron to apply its GPCR drug discovery technology platform, which uses conformationally selective VHH antibodies – ConfoBodies® – to stabilize GPCRs enabling the discovery of novel therapeutic antibody drug candidates. " Read more at the source #DrGPCR #GPCR
- Crinetics Pharmaceuticals announced the formation of an independently operated new company...
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- Sosei Heptares Enters Antibody Discovery Agreement with Twist Bioscience to Discover and Develop ...
Discovery Agreement with Twist Bioscience to Discover and Develop Novel Therapeutic Antibodies against GPCR world-leading StaR® (stabilized receptor) platform to generate novel antibody leads to disease-relevant GPCR Cambridge, UK, 16 December 2021 – Sosei Group Corporation (“the Company”; TSE: 4565), the world leader in GPCR-focused announced a strategic collaboration to discover therapeutic antibodies against G protein-coupled receptors (GPCR ) identified by Sosei Heptares . " Read more at the source #DrGPCR #GPCR #IndustryNews
- Addex's strategic partner The Janssen Pharmaceutical Companies of Johnson & Johnson, Inc. has...
potential global development of ADX71149 for the treatment of epilepsy. " Read more at the source #DrGPCR #GPCR
- Trevena Adds Seasoned Biopharma Commercial Executive to Senior Leadership Team
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- Dr. Kevin Pfleger and Dr. Elizabeth Johnstone were awarded one of the 2022 Diabetes Research...
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- Positive Recommendation for Use of TAVNEOS™ (avacopan) in ANCA Vasculitis Adopted by European ...
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- Dr. Thomas P. Sakmar receives an honorary doctorate from Karolinska Institute
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- Finding needles in haystacks: Omass unveils pipeline aimed at tough-to-drug targets
The targets, including G protein-coupled receptors (GPCRs), intracellular protein complexes and solute Read more at the source #DrGPCR #GPCR #IndustryNews
- California gold rush for Sosei Heptares
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- Dr. Alexander S. Hauser receives the Bachem award for peptide science
November 2021 Read more at the source #DrGPCR #GPCR #IndustryNews
- Search for safer pain relief advances with new engineered compounds
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- Neurocrine Biosciences Presents Data on Treatment of Adolescent Patients with Classic Congenital ...
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- Obesity-induced changes in human islet G protein-coupled receptor expression: Implications for ...
protein-coupled receptor expression: Implications for metabolic regulation G protein-coupled receptors (GPCRs ) are a large family of cell surface receptors that are the targets for many different classes of pharmacotherapy their secretion of insulin, and islet function can be modified by ligands acting at the large number of GPCRs and, in this review, we have compared expression of GPCR mRNAs in human islets obtained from normal We have also considered the likely outcomes on islet function that the altered GPCR expression status
- Role of G Protein-Coupled Receptors in Hepatic Stellate Cells and Approaches to Anti-Fibrotic ...
GPCRs represent major drug targets, as indicated by the fact that about 40% of all drugs currently used in clinical practice mediate their therapeutic effects by acting on GPCRs. Like many other organs, various GPCRs play a role in regulating liver function. It is predicted that more than 50 GPCRs are expressed in the liver. However, our knowledge of how GPCRs regulate liver metabolism and fibrosis in the different cell types