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133 items found for "AR"
- Ep 130 with Dr. Richard Premont
unsuccessful, but led to the identification of GRK5 and continued focus on GRKs (particularly GRKs 4,5,6) and arrestins For this, we have worked in three main areas: the regulation of G protein-coupled receptor signaling particularly by the G protein-coupled receptor kinase (GRK) – beta-arrestin system, the coordination
- Ep 92 with Dr. Stephane Angers
He is the recipient of the Canada Research Chair in Functional Architecture of Signal Transduction.
- Small-molecule targeting of GPCR-independent noncanonical G-protein signaling in cancer
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- Posters | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Anti-Tumorigenic Role of Brain Angiogenesis Inhibitor 3 (BAI3) in WNT-Activated Medulloblastomas Virginea de Araujo University of Alabama at Birmingham" About Virginea de Araujo Farias "Brain Angiogenesis Inhibitor (BAI (1, 2), Dutka Przemysław (1, 4), Siffer Gracie (3), Kossiakoff Anthony A. (1), Vafabakhsh Reza (3), Araç Kordon on the web Araç Laboratory at UChicago Deorphanization Of The Adhesion GPCRs GPR110 and GPR116 of Pharmacology, University of Michigan, Ann Arbor."
- Increased protease-activated receptor 1 autoantibodies are associated with severe COVID-19
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- Minireview: functional roles of tissue kallikrein, kinins, and kallikrein-related peptidases in lung cancer
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- Interaction with the cell adhesion molecule NEGR1 affects mGluR5 cell signalling
Ribeiro is the first or last author of 33 of these published articles. Dr. granted her research group a laboratory containing all the necessary equipment to perform state-of-the-art
- Comparison of infectious complications with BCMA-directed therapies in multiple myeloma
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- Stable Binding of Full-Length Chemerin is Driven by Negative Charges in the CMKLR1 N-terminus
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- Dynamic Phosphoproteomics of BRS3 Activation Reveals the Hippo Signaling Pathway for Cell Migration
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- A disturbed metabolite-GPCR axis is associated with microbial dysbiosis in IBD patients: Potential role of GPR109A in macrophages
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- Interplay between G protein-coupled receptors and nanotechnology
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- Severity of neurological long-COVID symptoms correlates with increased level of autoantibodies targeting vasoregulatory and autonomic nervous system receptors
ARB1 and ARB2 correlated negatively CERAD Trail Marking A and B (R ≤ -0.26, p ≤ 0.043), while CHRM3 correlated GPCR Create an account and get our contributors articles in your inbox Subscribe to the Dr.
- Pan-cancer functional analysis of somatic mutations in G protein-coupled receptors
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- Chemokine Physiology in Cancer
In this article we review current literature on the diversity of chemokine ligands and their cellular GPCR Create an account and get our contributors articles in your inbox Subscribe to the Dr.
- The landscape of cancer-rewired GPCR signaling axes
Authors Chakit Arora, Marin Matic, Luisa Bisceglia, Pierluigi Di Chiaro, Natalia De Oliveira Rosa, Francesco GPCR Create an account and get our contributors articles in your inbox Subscribe to the Dr.
- GPR56 signaling pathway network and its dynamics in the mesenchymal transition of glioblastoma
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- GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment
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- Plenary Lecture | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
For arrestin mediated biased signaling, we have proposed the “flute model” and “poly proline region docking theory” etc. to explain the arrestin mediated GPCR functions (Nature communications, 2015, 2021, 2022 We identified that arrestin can mediated AT1R/TRPC3 or M3R/TRPC3 coupling by forming a complex of AT1R /β-arrestin-1/PLCγ/TRPC3 or M3R//β-arrestin-1/TRPC3 (Nature communications, 2017, Nature communications We also identified that orphan receptor GPR64 forms complex with β-arrestin-1 and CFTR at apical membrane
- Regulator of G protein signaling 16 restrains apoptosis in colorectal cancer through disrupting TRAF6-TAB2-TAK1-JNK/p38 MAPK signaling
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- Ep 53 with Dr. Timo De Groof
During his last year of studies, Timo performed research in the biopharmaceutical company Argen X and
- CB2 stimulation of adipose resident ILC2s orchestrates immune balance and ameliorates type 2 diabetes mellitus
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- The orphan G protein-coupled receptor 141 expressed in myeloid cells functions as an inflammation suppressor
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- The power of many: Multilevel targeting of representative chemokine and metabolite GPCRs in personalized cancer therapy
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- Ep 118 with Dr. David Sykes
significant contribution to the understanding of agonist/ antagonist GPCR kinetic determinants in an area
- Chemokine Cxcl1-Cxcl2 heterodimer is a potent neutrophil chemoattractant
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- Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone
Authors Hsuan Lung, Kelly L Wentworth, Tania Moody, Ariane Zamarioli, Apsara Ram, Gauri Ganesh, Misun GPCR Create an account and get our contributors articles in your inbox Subscribe to the Dr.
- Comparative Analysis of the GNAI Family Genes in Glioblastoma through Transcriptomics and Single-Cell Technologies
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