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GI tract OR ligands drive an intracellular cascade that results in enhanced serotonin release (Braun T. The chimeric antigen receptor T cell therapy could also be a way to target tumor cells expressing ectopic

T. & Gainetdinov, R. R. Physiological roles of G protein-coupled receptor kinases and arrestins.

receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T

GPCRs in Oncology and Immunology A GPCR checkpoint drives CD8+ T cell dysfunction and immunotherapy failure

GPCRs in Immunology and Oncology The GPCR–Gαs–PKA signaling axis promotes T cell dysfunction and cancer

hedgehog pathway repression in tissue morphogenesis TIPE proteins control directed migration of human T

migration Respiratory infections predominate after day 100 following B-cell maturation antigen-directed CAR T-cell

Malignancy Bispecific antibodies targeting BCMA or GPRC5D are highly effective in relapsed myeloma after CAR T-cell

., Frielle, T., Bolanowski, M. A., Bennett, C. D., Rands, E., Diehl, R. E., Mumford, R.

Kenakin, T. and A.

for the treatment of mycosis fungoides or Sézary syndrome in adults which are subtypes of cutaneous T-cell

glutamatergic neurons GPCRs in Oncology and Immunology TIPE proteins control directed migration of human T

Naveen Thakur, Kenneth A Jacobson, Matthew T Eddy, et al. for their analysis on Membrane mimetic-dependence

T. Gilliland et. al 2013).

authors set out to investigate GalNAc-Ts candidates involved in CCR5 O-glycosylation with CHO GalNAc-T

between GPCRs and β-arrestins, paving the way for capturing challenging protein complexes (Böttke, T.