hormone receptor (TSHR) has been shown to regulate distinct cellular processes, including phospholipase C B., & Diniz, C. (2021). B., Gonçalves, J., & Diniz, C. (2019). C., Götz, K., Sungkaworn, T., Lohse, M. J., & Calebiro, D. (2016).

The head mesodermal cell couples FMRFamide neuropeptide signaling with rhythmic muscle contraction in C. Board of Directors Crinetics Pharmaceuticals Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)

SIGNIFICANCE STATEMENT In C. elegans , axon regeneration is positively regulated by the EGL-30 Gqα-JNK C. elegans secretes a family of small-molecule pheromones called ascarosides, which serve various functions

from the coagulation and fibrinolytic cascades, as well as from inflammatory reactions, process the C-terminus

While GPCRs can exist as monomers, some types, like class C GPCRs, are obligate dimers, either as homodimers Graaf, C., et al., Glucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March

we show that GRKs generate distinct phosphorylation barcodes in intracellular loop 2 (ICL2) and the C

., & Tate, C. G. 2021). and β-arrestins, paving the way for capturing challenging protein complexes (Böttke, T., et al. 2020, Aydin M. et al. 1999), while dual knockout is lethal (Schmid, C. L., & Bohn, L. M. 2009).

Middle-Down Mass Spectrometry Reveals Activity-Modifying Phosphorylation Barcode in a Class C G Protein-Coupled Tracking N- and C-termini of C. elegans polycystin-1 reveals their distinct targeting requirements and

consequences of spatial, temporal and ligand bias of G protein-coupled receptors Inverse Regulation of C-C

Moreover, we assess β-arrestin conformational changes that are induced specifically by proximal and distal C-terminal

divided into six classes based on amino acid sequence similarities, but only four of the classes (A, B, C,

activated, ERKs translocate to the nucleus, phosphorylating various transcription factors, including ETS, c-Jun Lu, N., & Malemud, C. J. (2019).

Although it has been established that the palmitoylation of the C-terminal Go protein is essential for

., & Humblet, C. (1998). G-protein coupled receptors: models, mutagenesis, and drug design. C., Sykes, D. A., Viray, A. E., Vitale, R. M., Tomašević, N., ... & Carreira, E. M. (2024).

Receptor Expression Pharmacokinetics and Pharmacodynamics of Burixafor Hydrobromide (GPC-100), a Novel C-X-C

CCR2 canonical signaling requires the activation of Gαiβγ, followed by phosphorylation of the receptor C constitutively interacts with β-arrestin2, and constitutively internalizes in a β-arrestin2–dependent manner (C. Volpe et al. 2012); it dampens the inflammatory response when needed (C. A. H.

October 2022 "Recently determined structures of class C G protein-coupled receptors (GPCRs) revealed

with the 2 cases we previously reported as follows: (a) elderly (74-87 years at diagnosis), (b) male, (c)

G protein-coupled receptor (GPCR), which is activated by an endogenous peptide GPR15L(25-81) and a C-terminal

generating highly refined model structures of C5aR2, respectively in free (inactive), complexed to C-terminal

In silico analyses done in this study with the NetOGlyc 4.0 prediction algorithm (Steentoft C et al. phosphosulfate (PAPS) donor to the hydroxyl group of a tyrosine residue of the protein chain (Seibert C glycosaminoglycans which have an established role in chemokine gradients and oligomerization (Deshauer C

November 2022 "Recently determined structures of class C G protein-coupled receptors (GPCRs) revealed

Point mutations are in the C-tail of PAR4 PH-binding domain; F347 L and D349A, but not E346A, abrogate

binding to βγ and decreased binding to regulator RGS2, and effectors p63RhoGEF-DH/PH and phospholipase C-β

C. Burger , Arthur Christopoulos , David M. Crinetics Pharmaceuticals Announces September 2024 Inducement Grants Under Nasdaq Listing Rule 5635(c)

(trans) function of the Adhesion GPCR Latrophilin-1 controls multiple processes in reproduction of C. (trans) function of the Adhesion GPCR Latrophilin-1 controls multiple processes in reproduction of C.

water flea Diaphanosoma celebensis genome, which were classified into five distinct classes (A, B, C,

some important clinical parameters such as alpha-fetoprotein and tumor grade in the HCC patients; (c)