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37 items found for "Ben Jones"
- Endogenous ligand recognition and structural transition of a human PTH receptor
properties: PTH evokes prolonged Gs activation, whereas PTHrP evokes transient Gs activation with reduced bone-resorption
- Functional modulation of PTH1R activation and signaling by RAMP2
hormone 1 receptor (PTH1R), a class B GPCR and an important modulator of mineral ion homeostasis and bone
- 📰 GPCR Weekly News, May 6 to 12, 2024
Oncology and Immunology Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone The orphan G protein-coupled receptor 141 expressed Summit May 16 - 19, 2024 | ASPET 2024 May 27 - 29, 2024 | SLAS Europe 2024 Conference and Exhibition June 2 - 7, 2024 | Chemotactic Cytokines June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein Mediated Signaling Networks June 25 - 29, 2024 | FENS Forum 2024 July 8 - 10, 2024 | 4th IRN i-GPCRnet Annual
- Involvement of various chemokine/chemokine receptor axes in trafficking and oriented locomotion ...
MSCs have several sources and they can be derived from the umbilical cord, adipose tissue, and bone marrow
- 📰 GPCR Weekly News, March 4 to 10, 2024
and Signaling Glu1022.53-Mediated Early Conformational Changes in the Process of Light-Induced Green Cone Summit May 16 - 19, 2024 | ASPET 2024 May 27 - 29, 2024 | SLAS Europe 2024 Conference and Exhibition June 2 - 7, 2024 | Chemotactic Cytokines June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein Mediated Signaling Networks June 25 - 29, 2024 | FENS Forum 2024 October 2024 | Biologics US 2024 October 2 -
- Extracellular signal-regulated kinases – a potential pathway for GPCR-targeted drug discovery
Extracellular Signal-Regulated Kinase: A Regulator of Cell Growth, Inflammation, Chondrocyte and Bone
- Therapeutic validation of an orphan G protein‐coupled receptor
Regarding the second question, there is still a lot to be done in respect to tool compounds to study
- Glyco-sulfo hotspots in the chemokine receptor system
In silico analyses done in this study with the NetOGlyc 4.0 prediction algorithm (Steentoft C et al.
- An overview of the compartmentalized GPCR Signaling: Relevance and Implications
Nature communications, 8(1), 443. https://doi.org/10.1038/s41467-017-00357-2 Jong, Y.