fundraising gives us the means to achieve our ambitions: to become a leading player in the field of brain

September 2022 "For decades, glioblastoma multiforme (GBM), a type of the most lethal brain tumor, has

Exclusive access to private groups  Over 30 recorded talks from Symposia - that's a lot of brain food To Design Novel GPCR- Targeted Antibody Therapeutics Using Generative AI Zombie Fungi Hijack Hosts’ Brains punctata GPCRs in Neuroscience Neuron specific quantitation of Gαolf expression and signaling in murine brain

in high-resolution techniques to investigate peptidergic transmission and expression throughout the brain

This compound has vastly reduced brain penetration and is devoid of significant off-target liability.

The adenosine A1 and A2A receptors are expressed in the human brain and have a proposed involvement in

The adenosine A1 and A2A receptors are expressed in the human brain and have a proposed involvement in

In other brain regions, astrocytes sense diverse neurotransmitters and neuromodulators and, in turn,

Mouse models have provided invaluable information on the roles for PKA subunits in brain and key metabolic

., & Kobilka, B. K. (2022).

Crinetics hires people with big brains and small egos.”

mechanisms N. meningitidis employ to manipulate the immune system, translocate the mucosal and blood-brain

TGR5 is widely distributed in the brain, lung, heart, liver, spleen, pancreas, kidney, stomach, jejunum

treatment of neuropathic pain, a debilitating condition caused by damage to the nerves outside of the brain

accumbens shell and structures in the prefrontal cortex and amygdala, which were previously linked to the brain

immune system, including neutrophils, monocytes, and macrophages in the periphery and microglia in the brain

New Insights into MRP3 Transporter Function "Glioblastoma is the most common and aggressive primary brain

G-protein coupled receptors (GPCRs) play a paramount role in diverse brain functions.

quantitative Western blot analysis of CB1 receptor expression on crude synaptosomes of the adult rat brain

) system in the European sea bass, Dicentrarchus labrax , which exerted an inhibitory action on the brain-pituitary-gonadal

However, the pharmacokinetic properties of DOI differed among sexes - brain and plasma concentrations

We found that Adgra1 is highly and exclusively expressed in the brain, suggesting that Adgra1 may be

and mGluR2-mediated increase in pathogenic tau but also show that β-arrestin1 levels are increased in brains

Recordings in brain slices have shown that co-activation using saturating concentrations of agonists

Mouse Models of Social Interaction and Cognitive Impairment GPCRs in Neuroscience The Drosophila blood-brain

Bryan Roth, Sudarshan Rajagopal, and Graeme Milligan. Save the date! Dr.

Neuroscience Dopaminergic Input Regulates the Sensitivity of Indirect Pathway Striatal Spiny Neurons to Brain-Derived

Bryan Roth, Peter Gmeiner, and Thomas P. Sakmar this week. For Dr.