Search Results
115 items found for "Bryan S Yung"
- Ep 131 with Dr. Richard Premont
Harrington Discovery Institute and Case Western Reserve University, where he studies GPCR regulation by S-nitrosylation by GIT/PIX scaffolding complexes during cellular signaling, and characterizing the role of protein S-nitrosylation
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- Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1 inhibitor onvansertib in combination with decitabine in relapsed or refractory acute myeloid leukemia
Authors Peter J P Croucher , Maya Ridinger , Pamela S Becker , Tara L Lin , Sandra L Silberman , Eunice S Wang , Amer M Zeidan Tags AML , Biomarker , Hypomethylating agents , Onvansertib , PLK1 , Splicing
- Ep 09 with Lauren Celano
GPCR podcast episode, we sat down to chat with Lauren Celano to talk about career options for Ph.D.’s.
- Ep 129 with Dr. Kaavya Krishna Kumar
Brian Kobilka's lab at Stanford University, USA.
- Respiratory infections predominate after day 100 following B-cell maturation antigen-directed CAR T-cell therapy
Authors Jessica S Little , Megha Tandon , Joseph Seungpyo Hong , Omar Nadeem , Adam S Sperling , Noopur
- Expanding role of CXCR2 and therapeutic potential of CXCR2 antagonists in inflammatory diseases and cancers
be used as a biomarker and a new target for diabetes and that CXCR2 antagonists may also attenuate lung coronavirus disease 2019 (COVID-19). " Authors Yishi Xie , Wenbin Kuang , Dawei Wang , Kai Yuan , Peng Yang
- Using food perception and bioamine signaling networks to slow aging
Miller 1, Shijiao Huang 1, Elizabeth S. Dean 1, and Scott F. Leiser 1 1.
- Ep 111 with Chloe Hicks
previous endeavors involved exploring the effect of subcellular location on the signaling profile of CXCR3’s
- Ep 88 with Dr. Hannes Schihada
council) PostDoc fellowship to Stockholm, Sweden, in order to focus my research on class Frizzled GPCR s
- Ep 139 with Dr Silvia Sposini
regulatory mechanisms of GPCR action, namely dimerization and membrane trafficking, in Dr Aylin Hanyaloglu 's
- Ep 137 with Dr. Josh Pottel
Brian Shoichet at UCSF.
- Deciphering a GPCR-lncRNA-miRNA Nexus: Identification of an Aberrant Therapeutic Target in Ovarian Cancer
Revathy Nadhan , Rohini Gomathinayagam , Muralidharan Jayaraman , Mingda Yan , Srishti Kashyap , Kar-Ming Fung , Chao Xu , Resham Bhattacharya , Priyabrata Mukherjee , Ciro Isidoro , Yong Sang Song , Danny N Dhanasekaran
- The β2-adrenergic receptor associates with CXCR4 multimers in human cancer cells
multimeric complexes larger than dimers in MDA-MB-231 human breast cancer cells and in HCC4006 human lung Junyi Liang , Mohamed Seghiri , Pradeep Kumar Singh , Hyeon Gyu Seo , Ji Yeong Lee , Yoonjung Jo , Yong
- Minireview: functional roles of tissue kallikrein, kinins, and kallikrein-related peptidases in lung cancer
Immunology Minireview: functional roles of tissue kallikrein, kinins, and kallikrein-related peptidases in lung Published date July 3, 2023 Abstract "Despite campaigns and improvements in detection and treatment, lung One approach to treating patients suffering from lung cancer is to target surface receptors overexpressed Since lung cancer is often diagnosed in advanced stages, our efforts should focus on early diagnosis, Furthermore, their modulation could be considered as a promising approach in lung cancer therapeutics
- Ep 145 with Dr John Janetzko
Brian Kobilka at Stanford University at the end of 2017 for postdoctoral work. He chose Brian's lab due to his interest in studying conformational changes. John shared his experience of reaching out to and securing a position in Brian's lab. John explained the collaborative culture in Brian's lab, where individuals are encouraged to pursue projects
- GprC of the nematode-trapping fungus Arthrobotrys flagrans activates mitochondria and reprograms fungal cells for nematode hunting
Authors Xiaodi Hu, David S Hoffmann, Mai Wang, Lars Schuhmacher, Maria C Stroe, Birgit Schreckenberger
- Stretch regulates alveologenesis and homeostasis via mesenchymal Gαq/11-mediated TGFβ2 activation
Transforming growth factor-β (TGFβ) is essential for alveologenesis and lung repair, and the G protein To understand the role of mesenchymal Gαq/11 in lung development, we generated constitutive (Pdgfrb-Cre suppressed myofibroblast differentiation, altered mesenchymal cell synthetic function, and reduced lung TGFβ2 signalling in mesenchymal cells, which is imperative for normal alveologenesis and maintenance of lung Tags Alveologenesis , Cyclical mechanical stretch , GPCR , Gαq/11 , Lung development , TGFβ .
- Student Flash Presentations | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Kussmaulallee 12, 91054 Erlangen, Germany 2 Developmental Genetics, Max-Planck-Institute for Heart and Lung Louis, 660 S. Euclid Ave, St. Louis, MO 63108, USA. Park B, Mohamed M, Li H, Elkholy A, Torrelli-Diljohn A, Kim JH, Jeong K, Murphy JM, Harvey CA, Dunlap S, James Bridges at National Jewish Health in Denver, CO researching molecular mechanisms of lung injury The current methods for testing KCC-07’s ability to reactivate ADGRB1 expression involve western blotting
- Ep 100 with Dr Caron Tribute Part 1
Brian Kolbilka (1987) Dr. Frederik Leeb-Lundberg (1984) Dr. Robert Lefkowitz (1973) Dr.
- Ep 84 with Rosie Dawaliby
Brian Kobilka's lab at Stanford University and the SFMB laboratory at the Université Libre de Bruxelles
- GPR176 promotes fibroblast-to-myofibroblast transition in organ fibrosis progression
In gene expression analysis of mouse lungs with induced fibrosis, eight GPCRs were identified, showing actin (αSMA), the profibrotic factor transforming growth factor β1 (TGFβ1), and collagen in a human lung Similar to the lung fibrosis model, increased Gpr176 expression was also observed in other organs affected expressed Gpr176 compared to alveolar epithelial cells, endothelial cells, and macrophages in the fibrotic lung
- A virally encoded GPCR drives glioblastoma through feed-forward activation of the SK1-S1P1 signaling axis
Bergkamp , Jeffrey R van Senten , Hendrik J Brink , Maarten P Bebelman , Jelle van den Bor , Tuğçe S
- Ep 70 with Dr. Stephen Ferguson
Brian Collier in the Department of Pharmacology and Therapeutics at McGill University (1994).
- Chemokine Physiology in Cancer
Authors Donovan Drouillard, Brian T Craig, Michael B Dwinell Tags Chemokine receptor; cell migration;
- Ep 27 with Dr. Robert J. Lefkowitz
Brian Kobilka . Bob doesn’t really need an introduction since his reputation precedes him.
- Severity of neurological long-COVID symptoms correlates with increased level of autoantibodies targeting vasoregulatory and autonomic nervous system receptors
Authors Felix S Seibert , Ulrik Stervbo , Lea Wiemers , Sarah Skrzypczyk , Maximillian Hogeweg , Sebastian
- Deletion of macrophage Gpr101 disrupts their phenotype and function dysregulating host immune responses in sterile and infectious inflammation
Authors Magdalena B Flak , Duco S Koenis , Maria Gonzalez-Nunez , Ana Chopo-Pizarro , Jesmond Dalli Tags