About Dr. At the high of the pandemic, the Dr. Dr. Bryan Roth, Dr. Robert Lefkowitz, Dr. Fiona Marshall, Dr. Sam Hoare, Dr. Graciela Pineyro, Dr. Debbie Hay, Dr. Randy Hall, tributes to Dr. Marc Caron with over 30 guests including Dr.

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Be our Guest In each episode, we chat with an expert about their career trajectory, discoveries, and

Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Structure-based discovery Dr. Peter Gmeiner received his Ph.D. from the University of Munich. Upon receiving his Dr. GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec

Dr. GPCR Podcast << Back to podcast list Dr. Brian has contributed to the discovery or development of 5 marketed drugs through his work spanning molecular Dr. He continues to pioneer in drug discovery studying GPCRs and other target classes. Dr. Brian Arey on the web LinkedIn ResearchGate Pubmed Dr.

Dr. GPCR Podcast << Back to podcast list Dr. Aurélien Rizk About Dr. Aurélien Rizk "Dr. Aurélien Rizk is a scientist and entrepreneur in drug discovery. discovery, Dr. Dr. They also discussed the challenges of system dependency in data and the need to express data in a uniform

Dr. GPCR Podcast << Back to podcast list Dr. Sudha Shenoy About Dr. Sudha Shenoy Dr. Lefkowitz (Nobel Laureate, 2012) at Duke University. Dr. Dr. Sudha Shenoy on the web Duke University Personal Reflections and Words of Wisdom: Story From Dr. Sudha Shenoy LinkedIn Pubmed Dr.

About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Dinner 1 Date & Time Thursday, November 2nd / 8:00 PM Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

Dr. GPCR Podcast << Back to podcast list Dr. Françoise Bachelerie About Dr. The team’s projects are devoted to the activation/function of CXCR4-ACKR3 (CXCR7) receptors of the CXCL12 chemokine, key effectors of the immune system, including their role in immunological disorders (e.g. In particular, FB contributed to the discovery that CXCL12 is the ligand for the CXCR4 receptor and can Françoise Bachelerie on the web INSERM ResearchGate SciSpace Loop LinkedIn Dr.

Dr. GPCR Podcast << Back to podcast list Dr. Steven Foord About Dr. He also discovered and championed a novel prostaglandin EP4 drug candidate for development. Dr. Steven Foord on the web LinkedIn Google Scholar Pubmed Dr.

Dr. GPCR Podcast << Back to podcast list Dr. Mark Connor About Dr. Undergraduate BSc with Honours in Pharmacology from University of Sydney (1987, snake neurotoxins), Ph.D. from Department Focus on study of drugs and toxins on GPCR (opioid, cannabinoid receptor) and ion channel (K, Ca, TRP in orthosteric and allosteric interactions, and still looking for some bias ... anywhere ... these days Dr. Mark Connor on the web Researchers Twitter Google Scholar Dr.

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Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Register AGPCR Newsletter Dr Up About the venue Discover Cinvestav, the host venue for the upcoming workshop.

< GPCR News < GPCRs in Oncology and Immunology Respiratory infections predominate after day 100 following B-cell maturation antigen-directed CAR T-cell therapy Published date September 26, 2023 Abstract "Infections (CAR) T-cell therapy and risks may differ between the early and late periods. Infections were recorded until day 365, if patients experienced symptoms with a microbiologic diagnosis CAR T-cell therapy, with 42 early infectious events (days, 0-100), and 22 late infectious events (days

< GPCR News < GPCRs in Oncology and Immunology Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion Published date March 21, 2023 Abstract " Pancreatic ductal adenocarcinoma (PDAC Analysing the main members of the PDAC extracellular purinome using publicly available databases discerned Using genetic modification and pharmacological strategies we demonstrate mechanistically that this ATP-driven DNA-PAINT super-resolution fluorescence microscopy reveals that P2Y 2 regulates the amount and distribution

Dr. GPCR Podcast << Back to podcast list Dr. GPCR Team About Dr. Yamina Berchiche Dr. Yamina A. Dr. Dr. GPCR About Dr. Shivani Sachdev Dr. Dr.

treatment in Parkinson's Disease Date & Time Friday, November 3rd / 9:20 AM Abstract Coming Soon About Ali Salahpour "Dr. Marc Caron at Duke University for his post-doctoral training. In the Caron lab, Dr. of the dopamine system, including the dopamine transporter (DAT), the Vesicular Monoamine Transporter du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec

< GPCR News < GPCRs in Oncology and Immunology GPR4 in the pH-dependent migration of melanoma cells in the tumor microenvironment Published date December 23, 2022 Abstract Due to its high metastatic potential , malignant melanoma is one of the deadliest skin cancers. GPCR Create an account and get our contributors articles in your inbox Subscribe to the Dr. Follow the Dr. GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

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Dr. GPCR Podcast << Back to podcast list Dr. Shivani Sachdev About Dr. Shivani Sachdev "Dr. Sachdev is an early career researcher in the National Institute of Diabetes and Digestive and Kidney Diseases at the National Institutes of Health. Dr. Dr. Shivani Sachdev on the web NIDDK ReseachGate Google Scholar LinkedIn Twitter Dr.

Dr. GPCR Podcast << Back to podcast list Dr. Paul Insel About this episode In 1975, Dr. During dinner with colleagues and Alfred Gillman , co-recipient of the 1994 Nobel Prize in Physiology designated to go to Gillman’s lab . Dr. Google PubMed Dr.

Dr. GPCR Podcast << Back to podcast list Dr. Richard Premont About Dr. Richard Premont "Dr. In 1992, he won a Helen Hay Whitney Foundation fellowship to support his post-doctoral work with Robert Lefkowitz and Marc Caron at Duke University. 2018 studying GPCRs and their signaling pathways in the liver and in liver disease. Dr. Richard Premont on the web Google Scholar LinkedIn Dr.

Dr. GPCR Podcast << Back to podcast list Dr. Graciela Pineyro About this episode: Dr. Graciela Pineyro is a professor of pharmacology at the department of pharmacology and physiology of the She has done extensive work on the molecular pharmacology of opioid receptors and is currently focusing Dr. Graciela Pineyro on the web Dr. Graciela Pineyro on LinkedIn Dr. Graciela Pineyro - University of Montreal Dr.

Dr. GPCR Podcast << Back to podcast list Dr. Bryan Roth About this episode Dr. Bryan Roth is the Michael Hooker Distinguished Professor of Pharmacology at the University of North Carolina He was determined to work on psychiatric disorders and persevered even when he was told several times Dr. Better Psychiatric Medications LinkedIn Bryan Roth on Twitter Roth Lab on Twitter Google Scholar Pubmed Dr

Program < Back to schedule Biased agonism at the GLP-1 receptor: from structure to animal models of disease Date & Time Friday, November 3rd / 11:05 AM Abstract Coming Soon About Patrick Sexton " Patrick Sexton is a NHMRC Senior Principal Research Fellow and Director, ARC Centre for Cryo-electron Microscopy of GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec

Immunology CCR6 as a Potential Target for Therapeutic Antibodies for the Treatment of Inflammatory Diseases This pathway is implicated in mechanisms related to many diseases, such as cancer, psoriasis, multiple To date, there are no drugs against CCR6 approved, and the development of small molecules against CCR6 is complicated due to the difficulty in screenings. GPCR Create an account and get our contributors articles in your inbox Subscribe to the Dr.

Published date May 30, 2023 Abstract "Objectives: Dental pulp stem cells (DPSCs) are a type of mesenchymal The dysfunction of DPSCs is related to the pathologic process of pulpitis. The participation of circular RNAs (circRNAs) in DPSC differentiation has been identified. This work focussed on exploring the functions and mechanism of circFKBP5 in DPSC dysfunction evoked by Materials and methods: The viability and apoptosis of human DPSCs (hDPSCs) were determined using Cell