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231 items found for "David Reiner-Link"
- CCR7 acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration
< GPCR News < GPCRs in Oncology and Immunology CCR7 acts as both a sensor and a sink for CCL19 to coordinate We show that CCR7 internalization also acts as an effective sink for the chemoattractant, dynamically
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- Ep 113 with Dr. Prasenjit Saha
Specifically, I am interested in understanding dysregulated G-protein coupled receptor (GPCR) signaling linked identify novel cellular target receptors of human gut microbe-derived metabolites that are pathologically linked receptors of a novel human gut microbe-derived metabolite called phenylacetylglutamine (PAG), which is linked Prasenjit Saha on the web Google Scholar Pubmed LinkedIn Dr.
- [1,2,4]Triazolo[1,5-c]pyrimidines as Tools to Investigate A3 Adenosine Receptors in Cancer Cell Lines
Immunology [1,2,4]Triazolo[1,5-c]pyrimidines as Tools to Investigate A3 Adenosine Receptors in Cancer Cell Lines Compound 20 has been tested on both A3 adenosine receptor positive cancer cell lines (CHO-A3AR transfected , THP1 and HCCT26) and in A3 negative cancer cell lines, showing no effect on the latter and a proliferative
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- Evolutionary diversity of CXCL16-CXCR6: Convergent substitutions and recurrent gene loss in sauropsids
This axis is linked to diseases like HIV/SIV, cancer, and COVID-19. sequencing of the lung shows a drop in TRM cells in species with CXCR6 loss, suggesting a possible link
- Transcriptomic analysis of human cytomegalovirus to survey the indirect effects on renal transplant recipients
Published date May 30, 2023 Abstract "Post-transplant human cytomegalovirus (HCMV) viremia has been linked study specifies some pathobiological pathways which are activated in HCMV active infection and could be linked
- Ep 86 with Nicole (Nicki) Perry-Hauser
Mutations in aGPCRs have been linked to various neuropsychiatric phenotypes, and my work will provide Nicole (Nicki) Perry-Hauser on the web LinkedIn Research Gate Pubmed Dr.
- GPR37 expression as a prognostic marker in gliomas: a bioinformatics-based analysis
protein-coupled receptor (GPCR) that is implicated in different physiological pathways in the brain, and has been linked expression was significantly higher in the glioma tissues compared to the normal brain tissues, and was linked
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- Short-chain fatty acids and cancer
Abstract "Short-chain fatty acids (SCFAs), derived from the diet and the microbiota, serve as crucial links
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- Enterococcus-derived tyramine hijacks α2A-adrenergic receptor in intestinal stem cells to exacerbate colitis
Our findings highlight a microbial ligand-GPCR pair in ISCs, revealing a causal link between microbial
- Pan-cancer functional analysis of somatic mutations in G protein-coupled receptors
targets such as the LPA and mGlu receptor families, but also discovered novel GPCRs which had not been linked
- Gi/o GPCRs drive the formation of actin-rich tunneling nanotubes in cancer cells via a Gβγ/PKCα/FARP1/Cdc42 axis
Altogether, our study pioneers a link between Gi/o-coupled GPCRs and TNT development, and sheds light
- Metabolic crosstalk: Extracellular ATP and the tumor microenvironment in cancer progression and therapy
ATP functions as a mighty damage-linked molecular pattern when released outside the cell, accumulating
- Agonists of galanin subtype 2 receptor may prevent pancreatic cancer and agonists of angiotensin II type 2 receptor may prevent colorectal cancer
Pathways linked to these tumor suppressor proteins may enhance immune surveillance, prevent carcinogenesis
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- The combination of brentuximab vedotin and chidamide synergistically suppresses the proliferation of T-cell lymphoma cells through the enhancement of apoptosis
Brentuximab vedotin (BV), an anti-CD30 monoclonal antibody linked to a microtubule-disrupting agent,
- SSTR2 positively associates with EGFR and predicts poor prognosis in nasopharyngeal carcinoma
receptor (EGFR) belongs to the receptor tyrosine kinases family and overexpression of EGFR has been linked
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- Ep 120 with Brendan Wilkins
characterise the molecular pharmacology of GPR146 and to validate the proposed ligands of GPR146 in line positions to begin in mid-2024" Brendan Wilkins on the web UNSW Sydney Google Scholar ResearchGate LinkedIn
- Ep 66 with Dr. Antony A. Boucard Jr
known as attention deficit hyperactivity disorder (ADHD) but also to a comorbid clinical manifestation linked Boucard Jr. on the web Website LinkedIn Researchgate Loop Academia Pubmed Adhesion GPCR Consortium University
- Ep 82 with Dr. Lauren M. Slosky
allosteric sites and exert pathway-specific effects on receptor signaling, they are exciting tools for linking Slosky on the web Twitter University of Minnesota Department Page LinkedIn Google Scholar PubMed Research
- Ep 136 with Murat Tunaboylu & Ben Holland
Murat Tunaboylu on the web Antiverse DSV Future of Drug Discovery Podcast Twist Bioscience LinkedIn Twitter pursued international strategic partnerships, managed IP matters, helped establish a manufacturing line analysis, and property prediction since 2017" Ben Holland on the web Antiverse The Antibody Society YT LinkedIn
- Trainee Symposium II
Back to schedule Trainee Symposium II Date & Time Thursday, November 2nd / 3:00 PM - 4:00 PM Title: Linking