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75 items found for "Filippo Prencipe"
- Exscientia is 10 years old this July!
decade, such as the first-ever AI-designed drug candidates to enter clinical trials, the first AI-driven precision
- GPR110, a receptor for synaptamide, expressed in osteoclasts negatively regulates osteoclastogenesis
August 2022 "Bone remodeling is precisely regulated mainly by osteoblasts and osteoclasts.
- 📰 GPCR Weekly News, June 10 to 16, 2024
July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs HIGHLIGHT Principal
- Unlocking the Future of Medicine: Advancements in GPCR Research
Course Schedule and Details Every Thursday at 10 am EST Principles of Pharmacology in Drug Discovery Principles of Pharmacology in Drug Discovery II - Advanced Methods for the Optimization of Candidate
- A Chemical Biology Toolbox Targeting the Intracellular Binding Site of CCR9: Fluorescent Ligands ...
In a proof-of-principle study, we succeeded in showing that our CCR9-PROTAC is able to reduce CCR9 levels
- Dopamine D 1 receptor-mediated β-arrestin signaling: Insight from pharmacology, biology, behavior...
discuss the importance of understanding the translatability of cell and animal models to have more precise
- Exscientia and Sanofi Establish Strategic Research Collaboration to Develop AI-driven Pipeline ...
Exscientia and Sanofi Establish Strategic Research Collaboration to Develop AI-driven Pipeline of Precision-Engineered
- The Impact of CB1 Receptor on Nuclear Receptors in Skeletal Muscle Cells
Cannabinoids are abundant signaling compounds; their influence predominantly arises via engagement with the principal
- Engineered synaptic tools reveal localized cAMP signaling in synapse assembly
formation of both Schaffer-collateral and entorhinal-CA1/temporoammonic-path synapses, suggesting a general principle
- Nuclear localization of histamine receptor 2 in primary human lymphatic endothelial cells
Therefore, it is imperative to understand the precise molecular mechanism of H2R biology.
- 📰 GPCR Weekly News, March 6 to 12, 2023
Professor Dame Carol Robinson Received 2023 ASMS John.B.Fenn Award Exscientia Announces Expansion of its Precision Oncology Pipeline Exscientia to Present Data Highlighting Pipeline and Precision Medicine Platform at
- 📰 GPCR Weekly News, May 15 to 21, 2023
Manager Vice President, Medical Affairs Associate Scientist - Technology Senior Research Scientist/Principal
- APEX2/AUR Biosensor: A Powerful Tool for Protein Interaction and Trafficking
that allows scientists to monitor the agonist-induced trafficking of DOR to the lysosome with high precision
- Rescue of Cell Surface Expression and Signaling of Mutant Follicle-Stimulating Hormone Receptors
understanding of the effects of genetic mutations on GPCR function and provide a proof of therapeutic principle
- 📰 GPCR Weekly News, June 3 to June 9, 2024
July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs HIGHLIGHT Principal
- High GPER expression in triple-negative breast cancer is linked to pro-metastatic pathways and...
TNBC) is a particularly aggressive and heterogeneous disease with few effective targeted therapies and precision
- GPCRS: AN ODYSSEY FROM STRUCTURE, SIGNALING AND REGULATION TO THERAPEUTICS
exciting opportunities in the translational development of these findings to generate safe and effective precision
- Unlocking the Therapeutic Potential of Previously Undruggable GPCRs
problem, Orion Biotechnology (Orion) is introducing a novel solution driven by its PROcisionXᵀᴹ platform: precision-engineering These approaches include generating ligand analogs by precision engineering the natural small protein States of America, 101, 16460-16465. https://doi.org/10.1073/pnas.0404802101 · Initial work on precision et al. (2004) Science, 306, 485–487. https://doi.org/10.1126/science.1099288 · Use of a first precision-engineered , 199, 1525-1527. https://doi.org/10.1086/598685 · Demonstration that topically administered precision
- 📰 GPCR Weekly News, December 4 to 10, 2023
GPCR Jobs NEW Postdoctoral Fellow NEW Post-Doc Research Associate NEW Assistant/Associate Professor Principal
- 📰 GPCR Weekly News, June 24 to 30, 2024
Director GPCR Drug Discovery Biologist HIGHLIGHT Principal Scientist, In vitro pharmacology Post-Doctoral
- 📰 GPCR Weekly News, May 8 to 14, 2023
GPCR Jobs Vice President, Medical Affairs Associate Scientist - Technology Senior Research Scientist/Principal
- 📰 GPCR Weekly News, January 8 to 14, 2024
Post-Doctoral Fellow Postdoctoral Fellow Research Laboratory Specialist Associate Postdoctoral Scientist Principal
- 📰 GPCR Weekly News, January 1 to 7, 2024
GPCR Jobs NEW Postdoctoral Fellow NEW Research Laboratory Specialist Associate Postdoctoral Scientist Principal
- 📰 Breaking Down the Latest GPCR Discoveries: a Weekly Update (Nov 27-Dec 3, 2023)
Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Principal
- 📰 GPCR Weekly News, May 27 to June 2, 2024
July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs HIGHLIGHT Principal
- 📰 GPCR Weekly News, January 15 to 21, 2024
Post-Doctoral Fellow Postdoctoral Fellow Research Laboratory Specialist Associate Postdoctoral Scientist Principal
- 📰 GPCR Weekly News, December 18 to 31, 2023
20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Postdoctoral Scientist NEW Principal
- 📰 GPCR Weekly News, December 11 to 17, 2023
Junior Research Scientist Postdoctoral Fellow Post-Doc Research Associate Assistant/Associate Professor Principal