Search Results
52 items found for "Genome sequence"
- Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors
Targeted capture sequencing and copy number analysis of 36 genes and nontargeted proteomics analysis Targeted capture sequencing revealed GNAS as the only driver gene, as previously reported. Classification by consensus clustering using both RNA sequencing and proteomics revealed many similarities
- Ep 122 with Dr. Nicolas Gilles
His strongest expertise lies in therapeutic target identification and all the steps from venom manipulations
- G protein-coupled receptors related to autoimmunity in postural orthostatic tachycardia syndrome
To date, POTS is recognized as one of the sequelae of coronavirus disease 2019 (COVID-19) and its frequency
- Session V | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
adhe-sion G-protein coupled receptors (ADGRs), as this extracellular domain contains an integral agonistic sequence domains and found that this ADGR is resistant to autoproteolysis despite the presence of a canonical HLS sequence with classical molecular dynamics - to study the GAIN domain cleavage mechanism of ADGRL1 reveals the sequence By directly scanning and comparing energetic sequences of reaction steps, the most likely pathway and
- RGS20 promotes non-small cell lung carcinoma proliferation via autophagy activation and inhibition of the PKA-Hippo signaling pathway
Furthermore, Transcriptome sequencing was performed to show enrichment genes and pathways. Transcriptomic sequencing suggested the involvement of the Hippo signaling pathway in the action of RGS20
- Ep 124 with Gáspár Pándy-Szekeres
modeling pipeline for GPCRs and since have branched out to multiple areas of GPCR research such as sequence
- Ep 138 with Dr. Daniel Isom
pharmacologist and biophysicist, systems and synthetic biologist, technologist, heavy CRISPR user, protein sequence
- Ep 123 with Dr. Lukas Grätz
modeling pipeline for GPCRs and since have branched out to multiple areas of GPCR research such as sequence
- Comparative analysis of the occupancy of Histone H3 Lysine 4 methylation in the cells treated with TGFβ and Interferonγ
Interferonγ Published date June 28, 2023 Abstract "In this current study, we have compared our H3K4me3 Chip-Sequencing
- Orphan receptor GPR50 attenuates inflammation and insulin signaling in 3T3-L1 preadipocytes
GPR50 (G protein-coupled receptor 50) is an orphan GPCR that shares the highest sequence homology with
- The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure
Here, we cross-integrated large singe-cell RNA-sequencing datasets from CD8+ T cells covering 19 distinct
- Evolutionary diversity of CXCL16-CXCR6: Convergent substitutions and recurrent gene loss in sauropsids
Notably, single-cell RNA sequencing of the lung shows a drop in TRM cells in species with CXCR6 loss,
- Transcriptomic analysis of human cytomegalovirus to survey the indirect effects on renal transplant recipients
extracted from PBMCs of 2 RT patients with active HCMV and 2 RT patients without infection and then were sequenced
- Single cell G-protein coupled receptor profiling of Transcription factor 21 expressing activated kidney fibroblasts
Experimental approach: RNA sequencing and single cell qRT-PCR were performed on mouse kidneys after unilateral
- Ep 125 with Dr. Gregory Tall
PARs have an N-terminal leader sequence that is clipped by exogenous proteases to reveal a new N-terminus
- Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone
Single-cell RNA sequencing on long-bone stromal cells of 9-wk-old male ColI(2.3)+/Rs1+ mice and littermate
- Suppor Dr. GPCR Ecosystem
Frequency One time One time Monthly Monthly Amount $5.00 $5.00 $25.00 $25.00 $100.00 $100.00 $250.00
- Donation for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Frequency One time One time Amount $ 0/300 Please provide your company/organization information and your
- Ep 107 with Dr. Roger Sunahara
modulate orthosteric ligand binding and target sites that are often located in regions that display higher sequence
- Ep 136 with Murat Tunaboylu & Ben Holland
Mid-career, he has worked in finance and developed high-frequency trading systems.
- Session II | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
The short stachel sequence at the extreme N-terminal end of the CTF functions as a tethered agonist to
- Deciphering a GPCR-lncRNA-miRNA Nexus: Identification of an Aberrant Therapeutic Target in Ovarian Cancer
Mechanistically, UCA1 sequesters let-7 miRNAs, effectively neutralizing their tumor-suppressive functions
- Ep 146 with Dr Michael Feigin
an organoid system for the culture of normal and malignant pancreatic tissue, allowing advances in sequencing
- Posters | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
GPR56CD-KO mice were born at predicted Mendelian frequencies, appeared grossly indistinguishable from