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59 items found for "Jessica S Little"
- New role of β-arrestins in MOR signaling
Proc Natl Acad Sci U S A. 1993 Jun 15;90(12):5391-3. doi: 10.1073/pnas.90.12.5391. Faouzi A, Varga BR, Majumdar S. Biased Opioid Ligands. Shiraki A, Shimizu S.
- Finding needles in haystacks: Omass unveils pipeline aimed at tough-to-drug targets
November 2021 "Nov. 15, 2021 LONDON – There’s not yet proof of the pudding, but Omass Therapeutics Ltd.’s
- Dr. GPCR University registration is now open! Secure your spot now!
includes congrats to: Clementine E Philibert and Mikel Garcia-Marcos for their work on Smooth operator(s) challenges Modulating Vertebrate Physiology by Genomic Fine-Tuning of GPCR Functions Smooth operator(s)
- Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin...
Defensins and Mrgpra2 were critical for combating S. aureus infections and the formation of neutrophil
- OMass Therapeutics's founder, Carol Robinson, has been awarded the prestigious Louis-Jeantet ...
December 2021 OMass Therapeutics 's founder, Carol Robinson , has been awarded the prestigious Louis-Jeantet
- 📰 GPCR Weekly News, July 31 to August 6, 2023
Randy Hall's study: GPR37L1's role in shaping cortical astrocytes during development Dr. And Advance Novel Oral Small Molecule Medicines Targeting G Protein-Coupled Receptors Novo Nordisk A/S:
- VAMP2: a crucial player in the delivery of MOR to the synapse
Jurado, S., D. Goswami, Y. Zhang, A.J.M. Molina, T.C. Südhof, and R.C. Malenka. 2013. Schoch, S., F. Deak, A. K ´ onigstorfer, M. Mozhayeva, Y. Sara, T.C. Südhof, and ¨ E.T.
- Anosmin 1 N-terminal domains modulate prokineticin receptor 2 activation by prokineticin 2
domain (WAP) is necessary for this modulatory activity, although data from GST pull-down (glutathione-S-transferase
- Neurocrine Biosciences Presents Data on Treatment of Adolescent Patients with Classic Congenital ...
These data will be shared as an oral presentation by Ron S.
- Exploiting Dependence of Castration-Resistant Prostate Cancer on the Arginine Vasopressin ...
through cAMP/protein kinase A signaling, consistent with AVPR2 coupling to the G protein subunit alpha s.
- Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells...
The results provide rationale for considering a combination(s) of FDA-approved SFK (dasatinib) and MEK
- Adhesion GPCR Consortium Newsletter - May 2024
I still remember entering the Hall at Boston ́s Children Hospital, going to register and being asked No wonder why Mexican cuisine has obtained the coveted status of UNESCO ́s Intangible Cultural Heritage
- The Impact of CB1 Receptor on Nuclear Receptors in Skeletal Muscle Cells
Further research is required to fully delineate their role(s)."
- 📰 GPCR Weekly News - January 2 to 8, 2023
s Director Stephen A.
- Unveiling GPCR Priming: The Hidden Synergy in Cellular Signalling
Proc Natl Acad Sci U S A, 2020. 117(35): p. 21723-21730. 2.
- Class B1 GPCR Dimerization: Unveiling Its Role in Receptor Function and Signaling
Proc Natl Acad Sci U S A, 2012. 109 (45): p. 18607-12. 8.
- 📰 GPCR Weekly News, February 13 to 19, 2023
In Anesthesiology Neurocrine Biosciences discovers new muscarinic M4 receptor antagonists Alexander S.
- 📰 GPCR Buzz: August 5-11, 2024 | Top Highlights from DrGPCR University!
s Check out the details of each course below: Open to the Public: Enrollment is Now Available!
- 📰 GPCR Weekly News, November 6 to November 12, 2023
and cross-reactivity in tachykinin NK1 and NK2 receptors GPCR Binders, Drugs, and more Discovery of (S)
- 📰 GPCR Weekly News, April 29 to May 5, 2024
We got a little busy with all the major events at Dr.GPCR, so our weekly news looks slightly different
- 📰 GPCR Weekly News, November 13 to 19, 2023
receptor negatively modulates substance P responses by forming complex with Neurokinin-1 receptor NTR-1's
- Regulators of G-protein signaling: essential players in GPCR signaling
Hollinger, S. and J.R.
- Fentanyl activates ovarian cancer and alleviates chemotherapy-induced toxicity via opioid...
Although increasing evidence has suggested the direct role of fentanyl on cancer, little is known on
- Unlock the Future of GPCR Science: Breakthroughs and Courses Await | Sep 2 - Sep 8, 2024
Natural Products and Compounds: Potential Therapeutic Targets for the Treatment of Neurological Disease s
- GPR110, a receptor for synaptamide, expressed in osteoclasts negatively regulates osteoclastogenesis
Although some G-protein coupled receptors (GPCRs) were reported to play roles in osteoblast function, little
- A central alarm system that gates multi-sensory innate threat cues to the amygdala
Yet little is known about whether and how multi-sensory innate threat cues are integrated and conveyed
- G protein coupling and activation of the metabotropic GABAB heterodimer
However, little is known about the mechanism for GP coupling and activation for class C GPCRs.
- Conservation of Allosteric Ligand Binding Sites in G-Protein Coupled Receptors
However, ligands binding at the same location generally show little or no similarity, and the amino acid