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81 items found for "Ji'ou Gu"
- 📰 GPCR Weekly News, January 8 to 14, 2024
estrogen receptor (GPER)/GPR30 forms a complex with the β1-adrenergic receptor, a membrane-associated guanylate
- 📰 GPCR Weekly News, November 20 to 26, 2023
Alix Rouault as our special guest. Subscribe now! mechanism of Gαq regulation of PLCβ3-catalyzed PIP2 hydrolysis GPCR Binders, Drugs, and more Discovery of Guanfacine
- 📰 GPCR Weekly News, November 6 to November 12, 2023
Kathleen Caron, as our video guest, subscribe now!
- 📰 GPCR Weekly News, October 30 to November 4, 2023
GPCR Activation and Signaling The G protein alpha chaperone and guanine-nucleotide exchange factor RIC conformation and arrestin interaction Ready for the sheet: β-strand folding of phosphorylation clusters guides the ZINC database of natural products for specific, testosterone-like, OXER1 antagonists A 19F-qNMR-Guided
- 📰 GPCR Weekly News, October 16 to 22, 2023
Silvio Gutkind.
- 📰 GPCR Weekly News, September 25 to October 1, 2023
Michel Bouvier, J Silvio Gutkind, and team found that Gαs is essential for GRK selectivity and gene regulation
- 📰 GPCR Weekly News, August 28 to September 3, 2023
for (mutant) G protein-coupled receptors Reviews, GPCRs, and more RGS2 and female common diseases: a guard
- Decoding β-Arrestins: from Structure to function
evolutionary conservation of both isoforms from fish to mammals indicates their non-redundant roles (Gurevich V., & Gurevich, V. V. 2006). increased or reduced activity within distinct cell types or tissues, will undoubtedly provide valuable guidance
- 📰 GPCR Weekly News, July 24 to July 30, 2023
Lukas Grätz, David Gloriam, and Gunnar Schulte’s research on Unveiling pathway selectivity in Frizzleds
- 📰 GPCR Weekly News, June 26 to July 2, 2023
Modulation of GPCR receptors common to gut inflammatory diseases and neuronal disorders, Alzheimer's
- 📰 GPCR Weekly News, June 12 to 18, 2023
Silvio Gutkind.
- 📰 GPCR Weekly News, June 5 to 11, 2023
Ines Liebscher, Ross Cheloha and Silvio Gutkind.
- 📰 GPCR Weekly News, May 29 to June 4, 2023
Conformational flexibility of β-arrestins - How these scaffolding proteins guide and transform the functionality
- 📰 GPCR Weekly News, May 22 to 28, 2023
GPCR Binders, Drugs, and more Design of Drug Efficacy Guided by Free Energy Simulations of the β2 -Adrenoceptor
- Feeder or trigger – CCR2 as a scavenger and regulator of cell migration
Gurevich, et al. 2018; Y. A. Berchiche et al. 2011).
- 📰 GPCR Weekly News, March 27 to April 4, 2023
GPCR Binders, Drugs, and more Predicting allosteric sites using fast conformational sampling as guided Dietary compounds activate an insect gustatory receptor on enteroendocrine cells to elicit myosuppressin
- 📰 GPCR Weekly News, March 20 to 26, 2023
CCL5-producing migratory dendritic cells guide CCR5+ monocytes into the draining lymph nodes.
- 📰 GPCR Weekly News, March 13 to 19, 2023
GPCR Binders, Drugs, and more Design of Drug Efficacy Guided by Free Energy Simulations of the β2-Adrenoceptor
- 📰 GPCR Weekly News, February 27 to March 5, 2023
GPCRs in Cardiology, Endocrinology, and Taste Dietary compounds activate an insect gustatory receptor
- Regulators of G-protein signaling: essential players in GPCR signaling
This domain contains the catalytic core that catalyzes the hydrolysis of guanosine triphosphate (GTP) to guanosine diphosphate of the G protein α subunit promoting the switch from activated to an inactivated
- 📰 GPCR Weekly News, January 16 to 22, 2023
Industry News Addex Provides Corporate Update And Financial Guidance Structure Therapeutics Appoints
- Odorant receptors – a bit of smell for drug discovery
cascade that results in enhanced serotonin release (Braun T. et. al 2007), an important regulator of gut
- Overview of adhesion GPCRs self-activation
., Guo, C., Chen, Z., Huang, Z., & He, Y. (2022).
- Pharmacological targeting of cGAS/STING-YAP axis suppresses pathological angiogenesis and...
The cyclic guanosine monophosphate (GMP)-adenosine monophosphate (AMP) synthase (cGAS)-stimulator of
- The regulation of PKA signaling in obesity and in the maintenance of metabolic health
regulation of metabolic processes in adipose tissue, liver, pancreas, adrenal, skeletal muscle, and gut
- Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1
At high cholesterol concentrations, LYCHOS bound to the GATOR1 complex, a guanosine triphosphatase (GTPase
- Mechanistic Understanding of the Palmitoylation of Go Protein in the Allosteric Regulation of...
insights into the regulation of aGPCRs via post-translational modifications of the Go protein, and offers guidance
- Structural view of G protein-coupled receptor signaling in the retinal rod outer segment
of the rod phototransduction system highlights the potential roles of phosphodiesterase 6 (PDE6) and guanylate